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Short-term AT(1) blockade reduces age-associated LV hypertrophy.

Cardiovascular Week

| November 24, 2003 | COPYRIGHT 2009 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 NOV 24 - (NewsRx.com & NewsRx.net) -- Short-term AT(1) blockade reduces age-associated LV hypertrophy in mice.

Cardiologists in the United States conducted a study "to determine how short-term (12 weeks) angiotensin type 1 (AT(1)) block begun late in life affects aspects of myocardial biology and physiologic function altered by normal aging."

"Exercise capacity, myocardial morphology, histopathology, and coronary vascular function (degree of coronary vasodilation in response to adenosine) were evaluated in 53 Fischer 344 rats," explained K.W. Saupe and coauthors at the University of Wisconsin. "Adult (6 months of age) and old (21 months of age) rats were…

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Source: HighBeam Research, Short-term AT(1) blockade reduces age-associated LV hypertrophy.

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