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Anthrax vaccine confers protection against both bacilli and toxins.
2003 NOV 19 - (NewsRx.com & NewsRx.net) -- A dually active anthrax vaccine conferred protection against both bacilli and toxins.
According to a study from the United States, "Systemic anthrax is caused by unimpeded bacillar replication and toxin secretion. We developed a dually active anthrax vaccine (DAAV) that confers simultaneous protection against both bacilli and toxins. DAAV was constructed by conjugating capsular poly-gamma-D-glutamic acid (PGA) to protective antigen (PA), converting the weakly immunogenic PGA to a potent immunogen, and synergistically enhancing the humoral response to PA."
"PGA-specific antibodies bound to encapsulated bacilli and promoted the killing of bacilli by complement," reported Gi-Eun Rhie and colleagues at Harvard University. "PA-specific antibodies neutralized toxin activity and protected immunized mice against lethal challenge with anthrax toxin. Thus, DAAV combines both antibacterial and antitoxic components in a single vaccine against anthrax. DAAV introduces a vaccine design that may be ...
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- Magazine article from: British Medical Journal Marwick, Charles March 16, 2002 700+ words
The anthrax vaccine licensed in the United...The need for an anthrax vaccine became a national...Marwick Washington The Anthrax Vaccine: Is it Safe? Does...is available on the National Academy Press website: www...
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...inoculations of the anthrax vaccine. By the fourth...to explain the anthrax vaccine. The Pentagon and...Citing a 2002 National Academy of Sciences study...Grabenstein said that the anthrax vaccine posed no greater...
- Vical Announces Publication of Anthrax Vaccine Protection Data.
- Press release article from: PR Newswire September 14, 2004 700+ words
...reviewed data from the company's anthrax vaccine challenge study in rabbits were published...14 issue of the Proceedings of the National Academy of Sciences (PNAS). The novel DNA...The successful testing of our anthrax vaccine in rabbits is an important milestone...
- Vical announces publication of anthrax vaccine protection data.
- News wire article from: Asia Africa Intelligence Wire September 14, 2004 700+ words
...announced that peer-reviewed data from the company's anthrax vaccine challenge study in rabbits were published in the 14 Sep 2004 issue of the Proceedings of the National Academy of Sciences (PNAS). The novel DNA-based vaccine being...
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- News wire article from: The America's Intelligence Wire December 15, 2004 700+ words
...Should all Americans get an anthrax vaccine to prevent against a possible...believes that the army's anthrax vaccine physically destroyed him...human safety studies to the National Academy of Sciences, the country...considering the matter that the anthrax vaccine is as ...
- Anthrax vaccine has long, thorny history.(The Seattle Times)
- Newspaper article from: Knight Ridder/Tribune News Service Rivera, Ray November 1, 2001 700+ words
...s illness to the anthrax vaccine, but Rugo is convinced...workers have received anthrax vaccine for 10-20 or more...a branch of the National Academy of Sciences) concluded...concluded that the anthrax vaccine's "efficacy against...
- Anthrax vaccine has long, thorny history.
- News wire article from: Seattle Times (Seattle, WA) October 27, 2001 700+ words
...s illness to the anthrax vaccine, but Rugo is convinced...workers have received anthrax vaccine for 10-20 or more...a branch of the National Academy of Sciences) concluded...concluded that the anthrax vaccine's "efficacy against...
- BioWar: Anthrax vaccine still needs study.(UPI Science Report)
- News wire article from: UPI Perspectives April 7, 2005 700+ words
...about whether the anthrax vaccine used by the Department...So it is not that anthrax vaccine is improving people...deployment and anthrax vaccine go together. Deployers...part of the National Academy of Sciences...
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- News wire article from: Ascribe Higher Education News Service December 19, 2005 700+ words
...19 (AScribe Newswire) -- Enough anthrax vaccine to inoculate everyone in the United...produce 360 million doses in a year. "Anthrax vaccine is very much in need, primarily because...been exposed. The next step for the anthrax vaccine would involve a company working with...
- Anthrax vaccine gets makeover.(Double Shot)
- Magazine article from: Science News Seppa, N. September 6, 2003 700+ words
...upcoming issue of the Proceedings of the National Academy of Sciences. "It's a double whammy...use, Fischetti says. The current anthrax vaccine requires six shots over 18 months...colleagues strive to develop a better anthrax vaccine, other scientists are still trying...
Source: HighBeam Research, Anthrax vaccine confers protection against both bacilli and toxins.