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Lentinan stimulates host defense against tuberculosis infection.
2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Given prior to infection, Lentinan stimulates host defense against M. tuberculosis in mice.
According to recent research from Bulgaria, the "protective effects of Lentinan (Ajinomoto, Japan) against Mycobacterium tuberculosis infection were studied by in vitro and in vivo mouse models."
"The effectiveness of Lentinan administrated intraperitoneally (i.p.) before infection at a dose of 1 mg/kg three times at two-day intervals was monitored in vivo by several parameters (body temperature; spleen weight; CFU counts of M. tuberculosis in spleen, liver and lung; and histomorphological observations)," explained N. Markova and coauthors working at the Bulgarian Academy of Sciences in Sofia.
"Peritoneal macrophages obtained from animals treated with Lentinan were greatly stimulated, as assayed by establishing their number, acid phosphatase activity, H[subscript]2O[subscript]2 production and killing ability against M. ...
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...non-modified PEI," wrote R. Tzoneva and colleagues, Bulgarian Academy of Science. The researchers concluded: "However, overall...information, contact R. Tzoneva, Institute of Biophysics, Bulgarian Academy of Sciences, Acad G Bonchev St., Bl 108, Sofia 1113...
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...chalcone action," wrote K.L. Lahtchev and colleagues, Bulgarian Academy of Science (see also Antifungals). The researchers concluded...Lahtchev, The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, Acad G Bonchev Street, Block 26, Sofia...
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...alkylated protein," wrote M.I. Dimitrov and colleagues, Bulgarian Academy of Science. The researchers concluded: "Additionally...information, contact M.I. Dimitrov, Insitute of Biophysics, Bulgarian Academy of Sciences, Sofia, Bulgaria. Publisher contact information...
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...processing networks," wrote P. Nanova and colleagues, Bulgarian Academy of Science. The researchers concluded: "This study provides...Institute of Neurobiology (former Institute of Physiology), Bulgarian Academy of Sciences, Acad G Bonchev str, bl 23, 1113 Sofia...
