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Plasmodium vivax adapted to Aotus monkeys aids malaria vaccine development.
2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Discovery of a highly infective Plasmodium vivax strain adapted to Aotus monkeys will aid malaria vaccine development.
According to a study from Colombia, "The New World primate Aotus nancymaae is susceptible to infection by the human malaria parasite Plasmodium vivax and has therefore been recommended by the World Health Organization as a model for malaria vaccine candidate evaluation. We report the isolation, adaptation, titration, and genetic characterization of a R. vivax wild strain in splenectomized A. nancymaae monkeys."
"Parasitemia remained high after 22 passages, reaching 7.88% by Giemsa and Acridine Orange staining and Real-Time PCR determination, making this P. vivax strain a highly infective and reliable asset to be used in R. vivax biological studies and vaccine development," reported Yago Pico de Coana and collaborators at the Fundacion Instituto de Inmunologia de Colombia (FIDIC) and the ...
- Plasmodium vivax adapted to Aotus monkeys aids malaria vaccine development.
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