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Vaccine candidate for Venezuelan equine encephalitis identified.
2003 NOV 12 - (NewsRx.com & NewsRx.net) -- Researchers have identified a vaccine candidate for Venezuelan equine encephalitis to begin testing in human trials.
According to published research from the United States, "The central objective of this research was to test molecularly defined, live attenuated Venezuelan equine encephalitis virus (VEEV) vaccine candidates that were produced through precise genetic manipulation of rationally selected viral nucleotide sequences."
"Molecular clones of vaccine candidates were constructed by inserting either three independently attenuating mutations or a PE2 cleavage-signal mutation with a second-site resuscitating mutation into full-length cDNA clones," reported William D. Pratt and collaborators at the U.S. Army Medical Research Institute of Infectious Diseases, University of North Carolina, and AlphaVax, Inc. "Vaccine candidate viruses were recovered through DNA transcription and RNA transfection of cultured cells, and assessed in rodent and non-human primate models. Based ...
- Vaccine candidate for Venezuelan equine encephalitis identified.
- Newspaper article from: Drug Week November 14, 2003 700+ words
...identified a vaccine candidate for Venezuelan equine encephalitis to begin testing...AlphaVax, Inc. "Vaccine candidate viruses were...be the best vaccine candidate for further...Venezuelan equine encephalitis: testing in...
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- Press release article from: PR Newswire March 22, 2006 700+ words
...company, for evaluation of the Venezuelan equine encephalitis (VEE) vaccine candidate V3526. VEE is a mosquito-transmitted...tolerability and immunogenicity of the vaccine candidate in healthy volunteers between the ages...
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- Magazine article from: Southern Medical Journal December 1, 2001 700+ words
PSY1 EASTERN EQUINE ENCEPHALITIS PRESENTING AS PSYCHOSIS...returned positive for eastern equine encephalitis virus, IgM 1:32 and IgG...noted a recent cluster of equine encephalitis in the cattle population as...
- Equine encephalitis virus adaptation to epizootic vectors influence spread.
- Newspaper article from: Drug Week December 31, 2004 700+ words
...NewsRx.net) -- Venezuelan equine encephalitis virus adaptation to epizootic vectors...mediates emergence of Venezuelan equine encephalitis virus (VEEV) from enzootic progenitors...enzootic (Subtype ID) Venezuelan equine encephalitis viruses: Evidence for epizootic...
- Mosquitoes in Sunland Park found carrying equine encephalitis.
- Newspaper article from: Las Cruces Sun-News (Las Cruces, NM) July 15, 2005 700+ words
...were found to be carrying Western equine encephalitis virus, which, in a small percentage...have been no human cases of Western equine encephalitis in the state this year or last year...protect his animals from Western equine encephalitis. "All of the horse owners are...
- Venezuelan equine encephalitis virus transmission and effect on pathogenesis.
- Magazine article from: Emerging Infectious Diseases Smith, Darci R. Aguilar, Patricia V. Coffey, Lark L. Gromowski, Gregory D. Wang, Eryu Weaver, Scott C. August 1, 2006 700+ words
...compared the amount of Venezuelan equine encephalitis virus collected from the saliva...log.sub.10] PFU of eastern equine encephalitis virus is deposited into capillary...estimated that the epidemic Venezuelan equine encephalitis virus (VEEV) vector, Aedes...
- Biotech company awarded contract to develop vaccine for equine encephalitis.
- Newspaper article from: Frederick News-Post (Frederick, MD) March 12, 2007 700+ words
...develop a DNA vaccine for equine encephalitis. The United States Department...several vaccine candidates for equine encephalitis using Ichor's DNA vaccine delivery system. Venezuelan equine encephalitis virus, Eastern equine encephalitis...
