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2003 NOV 6 - (NewsRx.com & NewsRx.net) -- Duloxetine reduces stress urinary incontinence episodes in study participants.
According to published research from the United States, "stress urinary incontinence (SUI) is the accidental leakage of urine associated with physical activities such as running, jumping or lifting or with sneezing and coughing. For many patients it can be a very bothersome symptom, causing social isolation, loss of self-esteem and increased financial outlays. Although there is currently no medication approved worldwide for the treatment of SUI, a variety of off-label agents are sometimes prescribed."
"Duloxetine (LY-248686; Eli Lilly), a new centrally acting compound with dual activity as a serotonin and noradrenaline re-uptake inhibitor, offers a promising new approach for treatment. Due to its inhibition of presynaptic neuron re-uptake of serotonin and noradrenaline in the sacral spinal cord, duloxetine is believed to increase the strength of urethral sphincter contractions and thereby prevent accidental urine leakage by increasing urethral closure pressure," described N.R. Zinner and colleagues, University of California Los Angeles, School of Medicine.
"In three ...
Source: HighBeam Research, Duloxetine reduces stress urinary incontinence episodes in study...