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Birth order in twins has no effect on HIV transmission risk.
2003 NOV 6 - (NewsRx.com & NewsRx.net) -- Contrary to previous reports, birth order in twins has no effect on HIV vertical transmission risk.
In a recent study, scientists in the United States "examined birth order and delivery route as risk factors for mother-to-child transmission of human immunodeficiency virus (HIV)-1 in 315 twin pairs born in Malawi during 1994-1998."
"No antiretroviral drugs were administered to these subjects," noted R.J. Biggar and coauthors working with the National Cancer Institute. "Infections were detected by polymerase chain reaction and were stratified as having occurred either in utero, perinatally, or postnatally."
Surprisingly, the investigators found that the "risk of in utero infection for 630 infants (39 infections) did not differ by birth order (first born, 6.3%; second born, 6.0%)."
"Similarly, in 260 vaginally delivered infants evaluated for perinatal infection (45 infections), risk did not differ by birth order (first born, 15.9%; second born, 18.7%)," although the "risk of perinatal infection was significantly lower in cesarean-delivered infants (odds ...
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Source: HighBeam Research, Birth order in twins has no effect on HIV transmission risk.