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Female HIV patients have higher risk of antiretroviral-induced ATAs.

Women's Health Weekly

| November 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 NOV 6 - (NewsRx.com & NewsRx.net) -- Female HIV patients have higher risk of antiretroviral-induced adipose tissue alterations (ATAs) compared to their male counterparts.

In a recent study from Italy, ATAs "were clinically assessed in 2,258 HIV-1-infected outpatients consecutively observed in six Italian clinical centers".

The results revealed that ATAs were "present in 29.5% of the men and 41.9% of the women," according to M. Galli and coauthors at the University of Milan.

"A logistic regression model including age, HIV disease Centers for Disease Control stage, CD4 cell counts, HIV RNA load, the duration of antiretroviral therapy, the number of drugs taken, and the use of d4T [stavudine] showed that men had a 0.47 adjusted risk of presenting with ATAs (95% CI: 0.38-0.58, p

"The risks of having ATAs (except circumscribed lipomas) in any body region, presenting with fat accumulation, or being affected by combined forms of ATA were also lower in men, whereas the risk of developing pure lipoatrophy was similar in the two genders," the ...

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Source: HighBeam Research, Female HIV patients have higher risk of antiretroviral-induced ATAs.

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