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2003 NOV 6 - (NewsRx.com & NewsRx.net) -- Factor V Leiden mutation does not correlate with stillbirth risk.
According to published research from Germany, "an association between the factor V Leiden variant and an increased risk of pregnancy loss has been reported. Most previous studies were performed with clinically recruited patients and controls. This approach may cause selection bias."
"The present analysis was performed with the aim to investigate the association between the factor V Leiden mutation and the risk of stillbirth in a population-based sample," wrote H. Volzke and colleagues, University of Greifswald, Institute of Epidemiology and Social Medcine.
"The Study of Health in Pomerania (SHIP) is a survey that was carried out in North East Germany. A random sample from the population aged 20 to 79 years was taken. The total SHIP population comprised 4310 participants. The presence of the factor V Leiden variant was determined by PCR and Mnl I digestion. The presence of the factor V Leiden variant was neither associated with the number of pregnancies nor with the number of children per women," investigators said.
"Data from 1768 females who had at least one pregnancy with known outcome was available for the present analysis. Seventy-three women (4.1%) reported at least one stillbirth. Women with and without ...
Source: HighBeam Research, Factor V Leiden mutation does not correlate with stillbirth risk.