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Association between oral contraceptive use, breast cancer may vary by histology.

Women's Health Weekly

| November 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 NOV 6 - (NewsRx.com & NewsRx.net) -- Association between oral contraceptive use, risk of breast cancer may vary by histologic type.

According to recent research published in the International Journal of Cancer, researchers "examined the association between oral contraceptive use and risk of specific breast cancer histopathologies in a large, multicenter, population-based, case-control study.

"Women younger than age 75 with a new diagnosis of invasive breast cancer were identified from four statewide tumor registries. We compared women with lobular (n=493) and ductal carcinoma (n=5,510) to randomly selected controls (n=9,311)," wrote L.M. Newcomer and colleagues, Fred Hutchinson Cancer Research Center, Department of Epidemiology.

"Odds ratios (OR) and 95% confidence intervals (CI) for each histologic type were estimated using polytomous logistic regression, adjusted for other breast cancer risk factors," the researchers wrote.

"Current oral contraceptive use was associated with increased risk of lobular carcinoma (OR =2.6, 95% CI =1.0-7.1) and there was a ...

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