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Dendritic cell vaccine induces T-cell immunity in stage IV melanoma patients.
2003 NOV 5 - (NewsRx.com & NewsRx.net) -- Single injection of CD34+ progenitor-derived dendritic cell vaccine can lead to induction of T-cell immunity in patients with stage IV melanoma.
According to a study from the United States, "There is evidence that dendritic cell (DC) vaccines induce tumor-specific immune responses that correlate with clinical responses. Little is known, however, about the kinetics of T-cell responses to antigens presented on DC vaccines. The authors vaccinated 18 HLA A*0201(+) patients with stage IV melanoma with CD34 HPC-derived DCs pulsed with six antigens: influenza matrix peptide (Flu-MP), KLH, and peptides derived from the four melanoma antigens: MART-1/Melan A, gp100, tyrosinase, and MAGE-3."
"A single DC vaccination was sufficient for induction of KLH-specific CD4 T-cell responses in five patients and Flu-MP-specific CD8 T-cell responses in eight patients," reported A. Karolina Palucka and collaborators at the Baylor Institute for Immunology Research, Rockefeller University, and the Memorial Sloan-Kettering Cancer Center. A single DC vaccine was sufficient for ...
- Aastrom Biosciences Receives NIH Grant for Dendritic Cell Vaccine Research; --...
- Press release article from: PR Newswire September 15, 2003 700+ words
...preclinical study for an ovarian cancer dendritic cell vaccine, Aastrom is preparing to begin dendritic cell clinical studies in collaboration...evaluate the completed patient-specific dendritic cell vaccine in human clinical trials. About Aastrom...
- NIH grant to be used for dendritic cell vaccine research.
- Newspaper article from: Immunotherapy Weekly October 15, 2003 700+ words
...preclinical study for an ovarian cancer dendritic cell vaccine, Aastrom is preparing to begin dendritic cell clinical studies in collaboration...evaluate the completed patient-specific dendritic cell vaccine in human clinical trials. Aastrom...
- Aastrom Biosciences Executes Evalaution Agreements With Leading German...
- Press release article from: PR Newswire April 19, 2001 700+ words
...The rapid progress of our dendritic cell product program underscores...in the development of novel dendritic cell vaccine approaches to cancer treatment...centers that are developing dendritic cell-based cancer vaccines...
- Aastrom's Dendritic Cell Vaccine Technology to Be Utilized in Duke University's...
- Press release article from: PR Newswire December 11, 2003 700+ words
...using Aastrom's DCV-II dendritic cell vaccine production kit and the AastromReplicell...access to Aastrom's unique dendritic cell vaccine production and cells, which...therapy treatments. In dendritic cell vaccine production, the platform...
- Dendritic cell vaccine induces T-cell immunity in stage IV melanoma patients.
- Newspaper article from: Drug Week November 7, 2003 700+ words
...CD34+ progenitor-derived dendritic cell vaccine can lead to induction of...CD34+ progenitor-derived dendritic cell vaccine can lead to induction of...Dermatology, Immunotherapy, Dendritic Cell Vaccine, and Oncology. This article...
- Argos Therapeutics and DC Bio Corp. Announce New Clinical Trial to Begin for...
- Press release article from: Business Wire November 8, 2005 700+ words
...proprietary RNA-loaded dendritic cell vaccine technology. The investigator...to using the personalized dendritic cell vaccine approach in treating patients...other Argos RNA-loaded dendritic cell vaccine clinical trials. Later...
- Dendritic Cell Vaccine Study Shows Promise in Helping Immune System Combat...
- Newspaper article from: Immunotherapy Weekly February 14, 2001 700+ words
...Los Angeles, California, have found that a dendritic cell "vaccine" was able to elicit a systemic immune response...median survival for patients who were given the dendritic cell vaccine was extended significantly." In fact, according...
- Dendritic cell vaccine to be used in trial for new cancer treatment.
- Newspaper article from: Cancer Vaccine Week January 5, 2004 700+ words
...clinical trial will evaluate a dendritic cell-based vaccine as a new treatment...using Aastrom's DCV-II dendritic cell vaccine production kit and the AastromReplicell...access to Aastrom's unique dendritic cell vaccine production and cells, which...
