Zidovudine and the natural history of the acquired immunodeficiency syndrome. (Periodical Report)

SOURCE: The New England Journal of Medicine, May 16, 1991;324(20):1412-1416.

Zidovudine (AZT) therapy is the factor most strongly associated with improved survival among people with AIDS, a population-based study indicates.

Johns Hopkins University researcher Richard D. Moore and colleagues studied AIDS survival trends using data from the Maryland Human Immunodeficiency Virus Information System. This system, funded through grants from federal and state agencies and from the Burroughs Wellcome Co., compiles data on patients reported to the Maryland Department of Health and Mental Hygiene by physicians. Also included in the system are data obtained through active, ongoing surveillance of clinical laboratories, …