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Immunotherapeutic approaches in ovarian cancer reviewed.

Vaccine Weekly

| October 08, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 OCT 8 - (NewsRx.com & NewsRx.net) -- Immunologic principles and immunotherapeutic approaches in ovarian cancer have been reviewed in a recent issue of Hematology - Oncology Clinics of North America.

According to researchers in the United States, "Ovarian tumors are immunogenic, and several ovarian-related antigens have been identified. The immunologic characteristics of the tumor microenvironment that may affect ovarian cancer growth are becoming increasingly understood."

"The type of immune-based approach selected to treat ovarian cancer depends on the tumor burden," said Keith L. Knutson and colleagues at the University of Washington in Seattle. "For minimal disease states, active vaccination may be useful for generating adequate protection from relapse. For more advanced stage disease states, more rigorous strategies may need to be applied, such as adoptive T-cell therapy, cytokine infusions, antibody therapy, or a combination of different techniques. The immunosuppressive environment observed during ...

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Source: HighBeam Research, Immunotherapeutic approaches in ovarian cancer reviewed.

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