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Corixa Corp. signs research, development, and license agreement.
2003 OCT 8 - (NewsRx.com & NewsRx.net) -- InNexus Biotechnology, Inc., (IXS), a monoclonal antibody-development company, and Corixa Corp. (CRXA), a developer of immunotherapeutic products, announced that the companies have entered into an antibody research, development, and license agreement.
The companies will develop lead antibody candidates combining InNexus' SuperAntibody Technology (SAT) with up to four antibodies from Corixa's therapeutic antibody development program.
InNexus' SAT technology can increase the binding strength of monoclonal antibodies, which allows them to cross-link their target antigen. This process can trigger "apoptosis," or cell suicide, or the enhancement of complement-dependent or immune-cell killing of pathogens, viruses, or tumor cells. InNexus' technology platform can also be used to confer novel properties to antibodies such as the ability to penetrate cells and bind to intracellular targets such as virus components (before assembly), and can allow antibodies to be converted into vaccines. The InNexus/Corixa collaboration will initially focus on enhancing the antitumor activity of selected antibody leads that are currently in development.
Under the terms of the agreement, following the potential creation of SuperAntibody ...
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Source: HighBeam Research, Corixa Corp. signs research, development, and license agreement.