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Lung cancer vaccines yield promising results in clinical trials.

Vaccine Weekly

| October 08, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 OCT 8 - (NewsRx.com & NewsRx.net) -- Lung cancer vaccines are yielding promising results in clinical trials.

"A number of cancer vaccine and gene therapy approaches are being evaluated in patients with lung cancer. Cancer vaccine strategies include GM-CSF gene-modified cancer cells, liposomal MUC1 peptide, anti-idiotype antibody targeting GD3, Mage-3 peptide, and mutant p53 pulsed dendritic cells among others," scientists in the United States report.

"Preliminary human trials have demonstrated immune responses as well as tumor regression in late stage disease," stated Kristen M. Hege at Cell Genesys, Inc. and David P. Carbone at the Vanderbilt-Ingram Cancer Center. "The largest human gene therapy experience in lung cancer is with intratumoral gene replacement therapy, predominantly with p53, but such approaches are limited to locoregional disease control. Earlier stage gene therapy programs ...

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Source: HighBeam Research, Lung cancer vaccines yield promising results in clinical trials.

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