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Matrix metalloproteinases appear to play a role in endometriosis.
2003 OCT 2 - (NewsRx.com & NewsRx.net) -- Matrix metalloproteinases may play a role in endometriosis; sometimes this may be in response to steroids.
"Retrograde menstruation represents a plausible explanation for the development of most cases of endometriosis; nevertheless, additional factors must contribute to the development of disease in only 10-20% of women. The discriminating factor(s) in determining the development of active endometriosis probably involves a complex array of potentially interactive influences including steroid exposure, immunological disturbances, genetic predisposition, and, perhaps, environmental toxin exposure," scientists in the United States report.
"Matrix metalloproteinases (MMPs), enzymes that mediate normal tissue turnover, including endometrial breakdown at menstruation, appear to be involved in the invasive establishment of the disease. In addition, several MMPs appear to be inappropriately expressed in the endometrium of women with this disease in association with a reduced sensitivity to progesterone," wrote K.G. Osteen and ...
- Cysteine proteinases, matrix metalloproteinases role in bone resorption...
- Newspaper article from: Life Science Weekly December 28, 2004 700+ words
...contribution of cysteine proteinases and matrix metalloproteinases to the resorption process in...utilize cysteine proteinases and matrix metalloproteinases to degrade the organic matrix...scapular osteoclasts utilizing matrix metalloproteinases to a greater extent than cysteine...
- Matrix metalloproteinases play role in weight loss-induced calciphylaxis.
- Newspaper article from: Obesity & Diabetes Week March 1, 2004 700+ words
...com & NewsRx.net) -- Matrix metalloproteinases appear to play a role in weight...found to have high levels of matrix metalloproteinases, which may have chemically altered...small vessels. Inhibitors of matrix metalloproteinases may be useful in the prevention...
- Matrix metalloproteinases perform multifunctional roles in multiple myeloma.
- Newspaper article from: Life Science Weekly November 16, 2004 700+ words
...com & NewsRx.net) -- Matrix metalloproteinases perform multifunctional roles...According to a study from Belgium, "matrix metalloproteinases (MMPs) are known to play a...Pathology (Multifunctional role of matrix metalloproteinases in multiple myeloma - A study...
- Matrix metalloproteinases are targets during experimental arthritis.
- Newspaper article from: Obesity, Fitness & Wellness Week June 26, 2004 700+ words
...com & NewsRx.net) -- Matrix metalloproteinases are targets for the immune system...six peptides were derived from matrix metalloproteinases (MMP), and only T cells responsive...in the Journal of Immunology (Matrix metalloproteinases as targets for the immune system...
- Matrix metalloproteinases lead specific functions in metastatic melanoma.
- Newspaper article from: Pharma Business Week February 16, 2004 700+ words
...com & NewsRx.net) -- Matrix metalloproteinases lead specific functions in metastatic...from Germany, "expression of matrix metalloproteinases (MMPs) and their activation...Cancer Research (Expression of matrix metalloproteinases in the microenvironment of spontaneous...
- Matrix metalloproteinases 2 and 7 expression increases with tumor stage.
- Newspaper article from: Cancer Weekly April 15, 2003 700+ words
...NewsRx.net) -- Matrix metalloproteinases 2 and 7 expression increases...with tumor stage. "Matrix metalloproteinases (MMPs) are associated...Reports (Expression of matrix metalloproteinases in human transitional...
- Membrane-type matrix metalloproteinases are elevated in gliomas.
- Newspaper article from: Pain & Central Nervous System Week May 19, 2003 700+ words
...Membrane-type matrix metalloproteinases are elevated in...from England, "Matrix metalloproteinases (MMPs) and tissue...membrane-type matrix metalloproteinases in gliomas revealed...
- Gabexate mesilate blocks matrix metalloproteinases to stop cancer invasion.
- Newspaper article from: Science Letter September 14, 2004 700+ words
...Gabexate mesilate blocks matrix metalloproteinases to stop cancer invasion. According...proteases. However, its role on matrix metalloproteinases (MMPs) has not been identified...and metastasis by reducing matrix metalloproteinases and angiogenesis. Clin Cancer...
