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Glycoprotein overexpression a biomarker of aggressive ovarian, uterine cancers.
2003 OCT 2 - (NewsRx.com & NewsRx.net) -- The detection of a specific protein molecule could help oncologists identify uterine and ovarian cancers with poor prognosis and thereby enable better disease management of women with aggressive uterine or ovarian cancer, researchers suggest.
Ovarian and uterine cancer is the most common cause of death from cancer-related deaths for women with gynecological malignant disease. The prognosis for women with uterine cancer is usually better than for women with ovarian cancer; some women, however, will develop aggressive tumors in either disease, which increases the risk of death.
Peter Altevogt from the German Cancer Research Center, Heidelberg, Germany, and colleagues investigated whether a protein molecule (L1 glycoprotein) known to be involved in the spreading of malignant tumors was associated with the development of aggressive tumors for uterine and ovarian cancer.
They reported their findings in the September 12, 2003, issue of the Lancet.
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