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Intestinal cell cycle dysregulation occurs during SIV infection.
2003 OCT 1 - (NewsRx.com & NewsRx.net) -- High-throughput gene expression profiling indicates dysregulation of intestinal cell cycle mediators and growth factors during primary simian immunodeficiency virus infection.
According to a study from the United States, "During primary simian immunodeficiency virus (SIV) infection, CD4+ T cells are severely depleted in gut-associated lymphoid tissue (GALT), while CD8+ T-cell numbers dramatically increase. To gain an understanding of the molecular basis of this disruption in T-cell homeostasis, host gene expression was monitored in longitudinal jejunum tissue biopsies from SIV-infected rhesus macaques by DNA microarray analysis."
"Transcription of cyclin E1, CDC2, retinoblastoma, transforming growth factor (TGF), fibroblast growth factor (FGF), and interleukin-2 was repressed while cyclins B1 and D2 and transcription factor E2F were upregulated, indicating a complex dysregulation of growth and proliferation within the intestinal mucosa," reported Michael D. George and colleagues at the University of California-Davis. "Innate, cell-mediated, and humoral immune responses were markedly upregulated in animals that significantly ...
- Intestinal cell cycle dysregulation occurs during SIV infection.
- Newspaper article from: Medical Letter on the CDC & FDA October 5, 2003 700+ words
...throughput gene expression profiling indicates...dysregulation of intestinal cell cycle mediators...intestinal gene expression during primary...throughput gene expression profiling indicates...dysregulation of intestinal cell cycle mediators...
- Intestinal cell line permissive to SARS coronavirus.
- Newspaper article from: Blood Weekly October 14, 2004 700+ words
...2004 OCT 14 - (NewsRx.com & NewsRx.net) -- An intestinal cell line is permissive to SARS coronavirus. "Severe acute...been detected. This study examined seven established human intestinal cell lines, DLD-1, HICT-116, HT-29, LoVo, LS-180...
- Reduced menin encourages intestinal cell tumorigenesis.
- Newspaper article from: Drug Week August 6, 2004 700+ words
2004 AUG 6 - (NewsRx.com & NewsRx.net) -- Reduced menin encourages intestinal cell tumorigenesis. "Menin, the product of the tumor suppressor gene MEN1, is widely expressed in mammalian endocrine and non...
- The intestinal beat goes on.(intestinal cell research)(Brief Article)
- Magazine article from: Science News Travis, John July 25, 1998 700+ words
To speed food on its digestive journey, intestines normally contract about a dozen times every minute. Researchers have long believed that a thin layer of specialized cells, the intestinal cells of Cajal, drive this steady rhythm. Now, a Canadian research team has isolated the hard-to-find cells
- CDX2 regulates LI-cadherin gene expression in gastrointestinal tract tissues.
- Newspaper article from: Proteomics Weekly January 13, 2003 700+ words
...exogenous CDX2, and gene expression changes relative...induced LI-cadherin gene expression, even in the presence...regulates LI-cadherin gene expression in normal, metaplastic...CDX2 function in intestinal cell fate determination...
- Gene clustering analysis may serve as molecular markers for gastric adenoma.
- Newspaper article from: Health & Medicine Week March 1, 2004 700+ words
...groups according to their gene-expression profiles. Nine genes...tumor size, exhibited gene-expression profiles of an intestinal cell lineage implicated in...prognostic values of these gene-expression profiles need to be evaluated...
- Gene Expression Profiling Life Science.
- Press release article from: M2 Presswire March 3, 2009 700+ words
...March 2009-Research and Markets: Gene Expression Profiling Life Science(C)1994...researchandmarkets.com/research/7fcde2/gene_expression_pr) has announced the addition of the "Gene Expression Profiling Life Science Dashboard...
- Genomic-Scale Gene Expression Analysis: Advancing from DNA to Disease.
- Press release article from: M2 Presswire December 17, 2002 700+ words
...and Markets Ltd: Genomic-Scale Gene Expression Analysis: Advancing from DNA to Disease...a-time" approach for analyzing gene expression is wholly inadequate. Not only would...sufficiently illuminate patterns of gene expression. Therefore, the current challenge...