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Immunization in tumor prevention reviewed.

Vaccine Weekly

| October 01, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 OCT 1 - (NewsRx.com & NewsRx.net) -- Researchers have published a review of immunization for tumor prevention in the journal International Immunopharmacology.

According to a study from Italy, "Recent experimental data suggest that immunity can be activated to prevent tumors. The rationale for prevention is strong because the setting is one endowed with an immune system that is neither impaired by tumor and treatment-induced suppression, nor tolerant to tumor-associated antigens."

"Oncogenic growth factor receptors are tumor antigens and rational targets for specific immunoprevention," said Guido Forni at the University of Turin and collaborators in Italy. "Successful prevention of mammary carcinomas in Her-2/neu transgenic mice is cited as an evidence of the validity of this approach. The specific properties of the Her-2/neu gene product as an antigen and the nature ...

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