AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Expression of anti-colorectal cancer polyclonal antibody library reported.
2003 OCT 1 - (NewsRx.com & NewsRx.net) -- Researchers have reported the expression of a prototypic anti-colorectal cancer polyclonal antibody library in mammalian cells.
"We describe the production of a prototypic polyclonal antibody library (PCAL), a standardized mixture of full-length IgG polyclonal antibodies for which the genes are available. The PCAL was generated by mass transfer of heavy and light chain variable region gene pairs, selected for binding to human colorectal cancer cells, from a Fab phage display vector to a mammalian IgG expression vector," scientists in the United States report.
"Following transfection of the IgG vector library into Sp2/0 myeloma cells, clones were characterized for IgG expression and binding to the colorectal cancer cells by ELISA, and for diversity by DNA fingerprinting, nucleotide sequencing, and immunoblot analysis," stated Liyan Chen and colleagues at Boston University. "The results showed that 76-84% of the library clones produce IgG and of those 72-79% bind antigen. Furthermore, ...
- Expression of anti-colorectal cancer polyclonal antibody library reported.
- Newspaper article from: Cancer Weekly September 30, 2003 700+ words
...prototypic anti-colorectal cancer polyclonal antibody library in mammalian...to normal tissue, polyclonal antibody libraries to cancer...prototypic anti-colorectal cancer polyclonal antibody library in mammalian...
- Symphogen and Biovitrum Initiate Phase 1 Clinical Trial with The First...
- Press release article from: Business Wire March 12, 2007 700+ words
...Biovitrum are developing a recombinant, polyclonal antibody for the treatment of Idiopathic...volunteers. Sym001 is a recombinant, polyclonal antibody product candidate, comprised of...Sym001 is the first ever recombinant polyclonal antibody to enter human clinical trials...
- Signet Laboratories Announces Availability of DJ-1 RUO Specific Polyclonal...
- Press release article from: PR Newswire September 10, 2004 700+ words
...EviMed), today announced the release of its DJ-1 RUO polyclonal antibody, a potential diagnostic for predicting the emergence...Manager at Signet. "Signet's rodent reactive DJ-1 polyclonal antibody, along with the previously released DJ-1 monoclonal...
- Anti-digoxin polyclonal antibody* is beneficial for the treatment of...
- Magazine article from: Inpharma Weekly Anonymous October 4, 2008 700+ words
Anti-digoxin polyclonal antibody* is beneficial for the treatment of pre-eclampsia, according...Other findings supported the theory that anti-digoxin polyclonal antibody binds to and removes from circulation endogenous digoxin...
- Laboratory releases of polyclonal antibody to predict emergence of Parkinson.
- Newspaper article from: Drug Week October 8, 2004 700+ words
...Laboratories, Inc., announced the release of its DJ-1 RUO polyclonal antibody, a potential diagnostic for predicting the emergence...manager at Signet. "Signet's rodent reactive DJ-1 polyclonal antibody, along with the previously released DJ-1 monoclonal...
- THP and SangStat Partner to Develop Humanized Polyclonal Antibody Drugs.
- Press release article from: Business Wire November 11, 2002 700+ words
...believes that it will be the first company to bring humanized polyclonal antibody preparations from genetically engineered animals to the...THP will establish a leadership position in the field of polyclonal antibody therapeutics." SangStat's commitment to THP includes...
- Symphogen and Meiji Seika Kaisha Enter Agreement for Recombinant Polyclonal...
- Press release article from: Business Wire December 11, 2006 700+ words
...technology, Symplexa, to develop a fully human recombinant polyclonal antibody (pAb) product candidate that targets a non-disclosed...clinical trials in 2007 and will be the first recombinant polyclonal antibody to enter clinical evaluation. Sym001 is targeting the...
- Polyclonal antibody against Human Parkin.(Immunological Reagents & Kits)
- Magazine article from: Bioscience Technology February 1, 2005 700+ words
...substantia nigra pars compacta. The gene encoding human parkin has been linked to an autosomal recessive form of PD. Polyclonal antibody to Human Parkin was raised using a synthetic peptide derived from mouse parkin sequence (304-322) and is effective...
