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Cancer vaccines present unique challenges.

Vaccine Weekly

| October 01, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 OCT 1 - (NewsRx.com & NewsRx.net) -- Cancer vaccines present unique challenges.

According to a study from the United States, "Whether vaccines are designed to prepare the immune system for the encounter with a pathogen or with cancer, certain common challenges need to be faced, such as what antigen and what adjuvant to use, what type of immune response to generate, and how to make it long lasting. Cancer, additionally, presents several unique hurdles. Cancer vaccines must overcome immune suppression exerted by the tumor, by previous therapy, or by the effects of advanced age of the patient."

"If used for cancer prevention, vaccines must elicit effective long-term memory without the potential of causing autoimmunity," said Olivera J. Finn and colleagues at the University of Pittsburgh. "This article addresses the common and the unique challenges to cancer vaccines and the progress that has been made in ...

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Source: HighBeam Research, Cancer vaccines present unique challenges.

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