AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
A misleading swelling of the tongue.(Oral pathology)
A 41 year old Indian man presented with a swelling on the tip of the tongue of six months' duration. He reported having irregular sharp teeth that caused repeated ulceration on the tongue, for which he had earlier sought orthodontic therapy. Intraoral examination revealed a 2 x 2 cm hard multilobulated swelling, exhibiting a smooth mucosal surface, situated at the tip of the oral tongue (fig 1). Cervical lymphadenopathy was absent. Systemic examination was normal. The haematological and biochemical parameters failed to reveal any abnormality and the chest radiograph was normal. A wide excision of the lesion with primary closure was carried out.
[FIGURE 1 OMITTED]
On gross examination, the specimen measured 2.5 x 2.5 x 1.5 cm and was covered with mucosa showing an irregular grey-white area measuring 1.5 x 1 cm extending close to deeper margin of excision. Microscopic examination revealed the lining stratified squamous epithelium with plenty of closely packed, well demarcated, non-caseating granulomas in the underlying connective tissue (fig 2). These granulomas were composed of epithelioid cells, few lymphocytes, occasional plasma cells, and multinucleated Langhan's and foreign body type of giant cells (fig 3). Some of the giant cells showed reddish-pink, spider-like, stellate inclusions (asteroid bodies) within the cytoplasm (fig 4). There was no evidence of necrosis.
[FIGURES 2-4 OMITTED]
QUESTIONS
(1) What is the differential diagnosis for this lesion?
(2) How will you establish a definitive diagnosis and suggest the investigations necessary for the same?
- Researchers from University of Michigan describe findings in differential...
- Newspaper article from: Medical Devices & Surgical Technology Week November 23, 2008 700+ words
...fifth rib. A broad clinical differential diagnosis prompted FNA to evaluate the...eosinophils, multinucleated giant cells and scattered Touton giant...should be considered in the differential diagnosis of any histocytic/fibrohistiocytic...
- Differential diagnosis
- Magazine article from: Dermatology Times Petrou, Ilya July 1, 2009 700+ words
...displayedavarietyof different cell types, including multinucleate giant cells, greatly enlarged (monster) cells, signet ring cells...Cheung, amelanotic melanoma should be considered in the differential diagnosis. He says it is important for dermatologists to understand...
- New differential diagnosis research from B.B. Shi et al outlined.(Report)
- Newspaper article from: Cancer Weekly September 29, 2009 700+ words
...pathogenic disease with difficult differential diagnosis from adrenal pheochromocytoma...literature is available to allow a differential diagnosis of these two conditions from each...evaluate the clinical profile, differential diagnosis and surgical treatments of both...
- The admissibility of differential diagnosis testimony to prove causation in...
- Law and Contemporary Problems Sanders, Joseph Machal-Fulks, Julie September 22, 2001 700+ words
...frequently goes by the name of "differential diagnosis," although some courts have more...it might call into question the differential diagnosis testimony of many physicians...more admissibility challenges to differential diagnosis testimony. T here is now a considerable...
- Research reports from National Cheng-Kung University provide new insights into...
- Newspaper article from: Biotech Week March 25, 2009 700+ words
Fresh data on differential diagnosis are presented in the report...clinicopathologic study of 17 cases and differential diagnosis from erythema nodosum...to identify features for differential diagnosis. Microscopically, the...
- New differential diagnosis study findings have been published by scientists at...
- Newspaper article from: Biotech Week October 7, 2009 700+ words
...Fukuoka, Japan report (see also Differential Diagnosis). "MCNs and IPMNs have the potential...ultrasonography (EUS) for the differential diagnosis of cystic tumors of the pancreas...cystic component were important for differential diagnosis of potentially malignant cystic...
- Reports outline differential diagnosis study findings from J.A. Koufman and...
- Newspaper article from: Biotech Week December 3, 2008 700+ words
Fresh data on differential diagnosis are presented in the report 'Differential diagnosis of paradoxical vocal fold movement...conducted a study "To present the differential diagnosis of paradoxical vocal fold movement...
- Daubert, doctors and differential diagnosis: treating medical causation...
- Magazine article from: Defense Counsel Journal Kent, Michael B., Jr. October 1, 1999 700+ words
...winnowing process, known as "differential diagnosis" in the medical community, coupled...Although Dr. Papano conducted a differential diagnosis to determine what did not cause...is the medical technique called differential diagnosis. It is a clinical procedure whereby...
