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Cross-reactivity found between dengue and Japanese encephalitis viruses.

Vaccine Weekly

| September 17, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan. All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 SEP 17 - (NewsRx.com & NewsRx.net) -- Antibody responses of Japanese dengue fever patients demonstrated cross-reactivity between dengue and Japanese encephalitis viruses.

According to published research from Japan, "Titers of antibodies to infecting dengue virus serotypes determined by serum neutralization assay were higher than those of antibody to Japanese encephalitis (JE) virus in Japanese dengue patients after disease day 8."

"Titers of antibody to dengue virus antigens determined by hemagglutination inhibition (HI) assay were higher in only 1 of 23 serum specimens after disease day 11," reported Ken-Ichiro Yamada and colleagues at the Institute of Infectious Diseases in Tokyo. "Thus, the neutralization test is more reliable than the HI test for serological diagnosis of dengue in countries where JE vaccination is widely used or JE is endemic."

Yamada and associates published their findings in ...

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Source: HighBeam Research, Cross-reactivity found between dengue and Japanese encephalitis...