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Genome-based screening approach to vaccine development designed.
2003 SEP 10 - (NewsRx.com & NewsRx.net) -- Researchers have designed a genome-based functional screening approach to vaccine development that combines in vitro assays and DNA immunization.
"A two-step screening strategy was developed to identify strong immunogenic polypeptides with putative vaccine and/or adjuvant activity," scientists in New Zealand report.
"In the first step, a mycobacterial genomic DNA library was screened in vitro to identify plasmids encoding polypeptides that stimulate splenocytes from mycobacteria-immunized mice and T cells from PPD-positive healthy donors to produce interferon-gamma," stated Alain Delcayre and colleagues at Genesis Research and Development. "In the second step, plasmids were selected for their ability to induce protective immunity in a mouse model of tuberculosis following DNA immunization. The potential of this approach is ...
- Genome-based screening approach to vaccine development designed.
- Newspaper article from: Biotech Week September 10, 2003 700+ words
...designed a genome-based functional screening approach to vaccine development that combines in vitro assays and DNA...Vaccine (A genome-based functional screening approach to vaccine development that combines in vitro assays and DNA...
- 'India's vaccine development sector to lead biopharma biz'.
- News wire article from: PTI - The Press Trust of India Ltd. December 27, 2005 700+ words
'India's vaccine development sector to lead biopharma biz...India as the future site for vaccine development," a study undertaken by...favourite destination for vaccine development," he said. "It's a win...
- Thailand announces breakthrough in HIV vaccine development
- News wire article from: Xinhua News Agency September 24, 2009 700+ words
...Thailand announces breakthrough in HIV vaccine development BANGKOK, Sept. 24 (Xinhua...announced the breakthrough in the HIV vaccine development -- the first time ever that there...important foundation for further HIV vaccine development in Thailand in the future," said...
- Vaccine development to prevent cytomegalovirus disease reviewed.
- Newspaper article from: Virus Weekly September 14, 2004 700+ words
...NewsRx.net) -- Scientists review vaccine development to prevent cytomegalovirus disease...its 1999 assessment of targets for vaccine development. The priority was based on the...needed to bring about successful vaccine development at a National Vaccine Program Office...
- International Scientific Conference Features Advances in Vaccine Development...
- Press release article from: Business Wire September 22, 2008 700+ words
...the inherent problems in existing vaccine development technologies," Dr. Yusibov said...of the success and viability of a vaccine development project is the choice of an appropriate...sessions covering new substrates for vaccine development through clinical trial case studies...
- Antigen selection based on expression aids vaccine development.
- Newspaper article from: Proteomics Weekly August 16, 2004 700+ words
...level during infection facilitates vaccine development for an intracellular pathogen...millions of people every year, but vaccine development has been hampered by the slow largely...that will substantially facilitate vaccine development for Salmonella and possibly other...
- Novavax Acquires Vaccine Development Division of DynCorp.
- Press release article from: PR Newswire August 11, 1999 700+ words
...Division's 45-Year Expertise in Vaccine Development and Manufacture to Develop Therapies...Division's extensive expertise in vaccine development and manufacturing to develop therapies...technology with the Division's vaccine development and manufacturing capabilities...
- IAVI Applauds Historic UN Security Council Session on AIDS in Africa; Calls...
- Press release article from: PR Newswire January 10, 2000 700+ words
...biotech industries to engage in vaccine development." "Smallpox was eradicated thanks...to expand its commitment to AIDS vaccine development and ultimate distribution. Without...IAVI's scientific program is the Vaccine Development Partnership, a collaborative model...