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2003 SEP 10 - (NewsRx.com & NewsRx.net) -- Two new investigational smallpox vaccines will be studied as part of a clinical trial starting soon at St. Louis University's Center for Vaccine Development. St. Louis University is the only location in the United States participating in the trial.
The investigational vaccines, manufactured by Massachusetts-based Acambis, Inc., will be compared with the existing smallpox vaccine, known as Dryvax. The new vaccines were produced using modern methods of cell cultivation. Dryvax, the same smallpox vaccine that was provided to all U.S. residents during the period of routine smallpox vaccination, hasn't been produced in many years.
"Although there has not been a case of smallpox in the United States since 1949, the U.S. government has determined that it is necessary to keep smallpox vaccine available, in case the disease is reintroduced through bioterrorism," said Sharon Frey, MD, principal investigator for the study and associate professor of internal medicine in the division of infectious ...