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Human serum-reactive epitopes in virus-like particles of HPV mapped.
2003 SEP 10 - (NewsRx.com & NewsRx.net) -- Human serum-reactive epitopes in virus-like particles of human papillomavirus types 16 and 11 have been mapped.
According to a study from Sweden and the United States, "Most human antibodies against HPV16 can be blocked by the monoclonal antibody H16.V5. To investigate whether H16.V5 and human sera recognize similar epitopes, hybrid capsids containing different parts of HPV16 and HPV11 were evaluated for reactivity with human sera."
"The antibody responses among HPV 16-/HPV11+sera to HPV11 and to hybrid capsids containing the HPV11 C-terminus were strongly correlated," reported Xiaohong Wang and collaborators at MAS University Hospital in Sweden and the Milton S. Hershey Medical Center in the United States. "The antibody responses among HPV 16+/HPV11-sera to HPV16 and to a hybrid containing the HPV16 C-terminus were correlated and there was also reactivity with a hybrid containing the H16.V5 epitope in the HPV11 backbone."
The researchers found, "Several HPV16-/11-children's sera were reactive with ...
- Human serum-reactive epitopes in virus-like particles of HPV mapped.
- Newspaper article from: Drug Week September 12, 2003 700+ words
...Human serum-reactive epitopes in virus-like particles...collaborators at MAS University Hospital in Sweden...of human serum-reactive epitopes in virus-like particles...Joakim Dillner, MAS University Hospital, Department...
- Demonstration of Cross-Reactive Epitopes Should Enhance Vaccine Development.
- Newspaper article from: Blood Weekly May 10, 2001 700+ words
...medical writer - By identifying cross-reactive epitopes on the surface of erythrocytes parasitized...team set out to identify cross-reactive epitopes on parasitized erythrocytes (PEs...Plasmodium falciparum contain cross-reactive epitopes," Proceedings of the National Academy...
- Demonstration of Cross-Reactive Epitopes Should Enhance Vaccine...
- Newspaper article from: Vaccine Weekly May 9, 2001 700+ words
...medical writer - By identifying cross-reactive epitopes on the surface of erythrocytes parasitized...team set out to identify cross-reactive epitopes on parasitized erythrocytes (PEs...Plasmodium falciparum contain cross-reactive epitopes," Proceedings of the National Academy...
- New anthrax immunology research from University of Oklahoma, Health Science...
- News wire article from: Bioterrorism Week November 2, 2009 700+ words
...factors are directed to non-cross-reactive epitopes,' are discussed in a new report...to the same assays. Major cross-reactive epitopes were identified as EF amino acids...are constituted by non-cross-reactive epitopes," wrote M.L. Nguyen and colleagues...
- Scientists Create First Successful Libraries of Avian Flu Virus Antibodies;...
- News wire article from: Ascribe Higher Education News Service April 14, 2008 700+ words
...another collaborator on the project. "Perhaps most importantly, these antibodies may be used to identify cross-reactive epitopes on the hemagglutinin protein of an influenza virus. Identification of such epitopes may allow the rational design of vaccines...
- Scientists Create First Successful Libraries of Avian Flu Virus Antibodies.
- Press release article from: Business Wire April 14, 2008 700+ words
...another collaborator on the project. "Perhaps most importantly, these antibodies may be used to identify cross-reactive epitopes on the hemagglutinin protein of an influenza virus. Identification of such epitopes may allow the rational design of vaccines...
- Antibodies against pneumococcal proteins developed.
- Newspaper article from: Biotech Week October 13, 2004 700+ words
...these proteins and pneumococcal carriage or infection was found. Presumably, this results from the presence of cross-reactive epitopes on commensal bacteria." Adrian and his coauthors published their study in Vaccine (Development of antibodies against...
- Nut allergens can be in large or small quantity, pan-reactive or specific.
- Newspaper article from: Drug Week November 7, 2003 700+ words
...triggering: Both native and recombinant nut allergens have been identified and characterized and, for some, the IgE-reactive epitopes described. "Some allergens, such as lipid transfer proteins, profilins, and members of the Bet v 1-related family...