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High-throughput antibody screening processes reviewed.

Vaccine Weekly

| September 10, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 SEP 10 - (NewsRx.com & NewsRx.net) -- Researchers have published a recent review of high-throughput antibody screening processes.

According to recent research published in the journal Trends in Biotechnology, "There are many ways in which the use of antibodies and antibody selection can be improved and developed for high-throughput characterization. Standard protocols, such as immunoprecipitation, western blotting and immunofluorescence, can be used with antibody fragments generated by display technologies. Together with novel approaches, such as antibody chips and intracellular immunization, these methods will yield useful proteomic data following adaptation of the protocols for increased reliability and robustness."

"To date, most work has focused on the use of standard, well-characterized commercial antibodies," said Andrew Bradbury and collaborators at Los Alamos National Laboratory, Pacific Northwest National Lab, and the University of California-San Francisco in the United States and the ...

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