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Helicobacter pylori vaccines ready for testing in humans.
2003 SEP 10 - (NewsRx.com & NewsRx.net) -- Helicobacter pylori vaccines that have shown promise in animal models need to be rigorously tested in humans.
"Several lines of evidence from experimental animal models of infection have clearly demonstrated the feasibility of a prophylactic and therapeutic vaccine against Helicobacter pylori. However, comparatively few clinical studies have been carried out to evaluate whether the positive results obtained in animals can be reproduced in humans. The preliminary results obtained with single component, mucosally delivered vaccines have shown very limited results thus far," scientists in Italy report.
"Very good immunogenicity and safety profiles are now being obtained with parenterally delivered, aluminum hydroxide-adjuvanted multicomponent candidate vaccines," said Paolo Ruggiero and colleagues at Chiron Srl. "For sure, better vaccine formulations, better antigen preparation(s), better adjuvants, and better delivery systems have to be designed and tested for safety and ...
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...et al on familial clustering of Helicobacter pylori was presumably intended to inform...et al. Familial clustering of Helicobacter pylori infection: population based study...Sternevald E. Eradication of Helicobacter pylori in functional dyspepsia: randomised...
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- Magazine article from: British Medical Journal March 9, 2002 700+ words
...Misiewicz in their review of managing Helicobacter pylori infection take a balanced view of...A, Misiewicz JJ. Management of Helicobacter pylori infection. BMJ 2001;323:1047...Roque M, Gabriel R, Pajares JM. Helicobacter pylori eradication: proton pump inhibitor...
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...originados por una bacteria llamada Helicobacter pylori. Este microorganismo se adquiere...ms de 10 aos se descubri que la Helicobacter pylori era uno de los motivos que producan...Primer Simposium Internacional sobre Helicobacter Pylori, realizado en la Fundacin Mdica...
Source: HighBeam Research, Helicobacter pylori vaccines ready for testing in humans.