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2003 SEP 4 - (NewsRx.com & NewsRx.net) -- Human chorionic gonadotropin is useful for detecting early pregnancy and complications; but its use has a few problems, too.
"Human chorionic gonadotropin (hCG) is a heterogeneous molecule that is the marker of choice for detecting pregnancy and indicating ectopic pregnancies and spontaneous abortions. This article describes the use of hCG in detecting pregnancy, and how pregnancy detection is complicated by the extreme variation in individual hCG results and by the varying structure of hCG," researchers in the United States report.
"The problems of false-positive pregnancy tests due to early pregnancy losses or heterophilic antibodies, and of false-negative pregnancy tests due to delayed implantation, are discussed. Different kinds of pregnancy tests, professional laboratory assays, point-of-care, and home devices are compared," wrote S. Davies and coauthors.
The researchers concluded: "The use of hCG measurement and ...