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Monoamine transporters are involved in several reproductive processes.
2003 SEP 4 - (NewsRx.com & NewsRx.net) -- Monoamine transporters are involved in several reproductive processes.
"The uterus is innervated by adrenergic sympathetic fibers, and the endometrium has a capability for endogenous monoamine synthesis. Extracellular monoamine levels are regulated primarily through re-uptake by specific membrane-bound transporter proteins dopamine transporter (DAT), norepinephrine transporter ( NET) and serotonin transporter (SERT). Intracellular storage of monoamines involves vesicular transporter proteins (VMAT1 and VMAT2)," scientists in Sweden report.
"This study explored gene expression of the monoamine transporters in normal endometrium throughout the menstrual cycle and early decidua. In-situ hybridization histochemistry revealed three general classes of expression patterns:
i) epithelial expression of NET mRNA;
ii) increasing stromal expression of VMAT2 mRNA in the proliferative phase; and
iii) increasing epithelial expression of VMAT2 mRNA during the secretory phase," wrote B. Bottalico and colleagues, University of Lund Hospital, Department of Obstetrics & Gynecology.
"Real time PCR showed low expression levels of NET in ...
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Source: HighBeam Research, Monoamine transporters are involved in several reproductive processes.