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Estrogen receptor expression is differential in gynecological tissues.
2003 SEP 4 - (NewsRx.com & NewsRx.net) -- Estrogen receptor expression is differential in gynecological tissues.
According to a study from the United States, "estrogen receptors are present in the urogenital tract. However, little is known about the quantitative distribution of the traditional estrogen receptor (ERalpha) mRNA and the recently identified ERbeta mRNA. By quantitative reverse transcription polymerase chain reaction analysis, the distributions of ERalpha and ERbeta mRNA in mouse urogenital tissues and their expression in selected urogenital tissues after oophorectomy, with or without estrogen replacement, were evaluated."
"ERalpha mRNA concentrations were higher in the ovary, oviduct, uterus and vagina than in the kidney, ureter or bladder (P
"After oophorectomy and estrogen replacement, significant changes were identified in ERalpha and ERbeta mRNA expression."
"ERalpha and ERbeta mRNA are differentially expressed in mouse urogenital tissues. Oophorectomy and estrogen replacement affect estrogen receptors differently in the bladder, vagina and uterus. These results may explain some tissue-specific responses to estrogen and ...
- Estrogen receptor expression is differential in gynecological tissues.
- Newspaper article from: OBGYN & Reproduction Week September 1, 2003 700+ words
...of the traditional estrogen receptor (ERalpha) mRNA and...Carley and colleagues, Mayo Clinic, Department of Obstetrics...estrogen and selective estrogen receptor modulators," researchers...K.C. Podratz, Mayo Clinic, Department of Obstetrics...
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...Immunohistochemical Detection of Estrogen Receptor Beta in Paraffin-Embedded Human Breast...ductal carcinomas, for the presence of estrogen receptor-beta (ER-beta) or estrogen receptor-alpha (ER-alpha). Tumors were...
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- Estrogen receptor is involved in neuroprotection in an ischemia model.
- Newspaper article from: OBGYN & Reproduction Week November 22, 2004 700+ words
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