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Symptoms, cirrhosis disease progression are known; cause and cure remain elusive.
2003 SEP 4 - (NewsRx.com & NewsRx.net) -- Some of the symptoms and disease progression are known for primary biliary cirrhosis, but the cause and cure, other than liver transplant, remain elusive.
According to published research from the United States, "Primary biliary cirrhosis is a chronic cholestatic liver disease of adults. This disorder is characterized histologically by chronic nonsuppurative destruction of interlobular bile ducts leading to advanced fibrosis, cirrhosis, and liver failure. The precise etiopathogenesis of primary biliary cirrhosis remains unknown, although dysregulation of the immune system and genetic susceptibility both seem to be important.
"Affected patients are typically middle-aged women with abnormal serum concentrations of alkaline phosphatase. Presence of antimitochondrial antibody in serum is almost diagnostic of the disorder. Identification of primary biliary cirrhosis is important, because effective treatment with ursodeoxycholic acid has been shown to halt disease progression and improve survival without the need for liver transplantation. However, ...
- Mayo Researchers Help Discover Genetic Cause for Primary Biliary Cirrhosis.
- News wire article from: Ascribe Higher Education News Service May 27, 2009 700+ words
...predisposes patients to develop primary biliary cirrhosis (http://www.mayoclinic.org/primary-biliary-cirrhosis/), a disease that...destroys their livers. Primary biliary cirrhosis has no known cause...
- Primary Biliary Cirrhosis
- Encyclopedia entry from: Gale Encyclopedia of Medicine, 3rd ed. Polsdorfer, J. January 1, 2006 700+ words
Primary Biliary Cirrhosis Definition Primary biliary cirrhosis is the gradual destruction of the biliary system...the body, creating a great variety of diseases. Primary biliary cirrhosis progressively destroys the system that drains bile...
- Genetics, environment affect risk for primary biliary...
- Magazine article from: Internal Medicine News Boschert, Sherry April 15, 2006 700+ words
...environmental risk factors for primary biliary cirrhosis. The findings were presented...in the United States. Primary biliary cirrhosis typically strikes women...found that the risk for primary biliary cirrhosis increased with a family...
- X-linked gene elements leave women vulnerable to primary biliary cirrhosis.
- Magazine article from: Women's Health Weekly April 1, 2004 700+ words
...leave women vulnerable to primary biliary cirrhosis. "The mechanisms that...female predominance of primary biliary cirrhosis (PBC) are uncertain...monosomy X in women with primary biliary cirrhosis. Lancet, 2004;363...
- Hemagen receives FDA clearance for test for primary biliary cirrhosis.
- Press release article from: Business Wire June 25, 1997 700+ words
...to screen patients for primary biliary cirrhosis, a disfunction of the...approximately 90 percent) with primary biliary cirrhosis," added Franzblau...chronic liver syndromes (primary biliary cirrhosis, chronic active hepatitis...
- Lactobacillus vaccination: Primary biliary cirrhosis?: case report
- Magazine article from: Reactions Weekly Anonymous October 18, 2008 700+ words
Primary biliary cirrhosis developed in a 39-year...compatible with stage 2-3 primary biliary cirrhosis, was evident from a liver...tolerance and the induction of primary biliary cirrhosis. Thus, lactobacillus vaccination...
- Primary biliary cirrhosis research at Mount Sinai advances due to trust, trials.
- Newspaper article from: Health & Medicine Week January 12, 2004 700+ words
...amp; NewsRx.net) -- Primary biliary cirrhosis research at Mount Sinai...individuals afflicted with primary biliary cirrhosis (PBC) first undergo...Center for the Study of Primary Biliary Cirrhosis at Mount Sinai, supported...
- Genetics, environment affect risk for primary biliary cirrhosis.
- Magazine article from: Skin & Allergy News Boschert, Sherry January 1, 2006 700+ words
...environmental risk factors for primary biliary cirrhosis. The findings were presented...in the United States. Primary biliary cirrhosis typically strikes women...found that the risk for primary biliary cirrhosis increased with a family...
