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Breast cancer, metastasis, growth reduced with i.v. bee venom therapy in murine model.

Women's Health Weekly

| September 04, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 SEP 4 - (NewsRx.com & NewsRx.net) -- In a mouse breast cancer model, intravenous but not intradermal bee venom reduced metastasis to lung.

According to published research from Croatia, "The possible tumor growth-inhibiting and metastasis-inhibiting effects of bee venom in mice and in tumor cell cultures were studied. The tumor was a transplantable mammary carcinoma (MCa) of CBA mouse.

"Intravenous administration of bee venom to mice significantly reduced the number of metastases in the lung. However, subcutaneous administration of bee venom did not reduce the number of lung metastases, indicating that the antitumor effect of the venom could be highly dependent on the route of injection as well as close contact between the components of the venom and the tumor cells, as was shown by in vitro studies on MCa cells. We also observed variations in immunological parameter induced by bee venom," wrote N. Orsolic and colleagues.

The researchers concluded: "We propose that bee venom has an indirect mechanism of tumor growth ...

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Source: HighBeam Research, Breast cancer, metastasis, growth reduced with i.v. bee venom therapy...

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