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Estradiol implants don't improve the urge syndrome in postmenopausal women.
2003 SEP 4 - (NewsRx.com & NewsRx.net) -- Estradiol implants don't improve the urge syndrome in postmenopausal women.
"The aim of this prospective double-blind randomized placebo-controlled trial was to determine the effect of systemic estrogen on the 'urge syndrome' in postmenopausal women. The trial took place in a tertiary referral urogynecology unit. Postmenopausal women with the 'urge syndrome' were randomly allocated to receive a 25 mg 17beta-estradiol implant or placebo implant," scientists in England reported.
"Serum estradiol levels and endometrial thickness were measured on entry to the trial and at 1, 3 and 6 months. The following outcome measures were employed: videocystourethrography, frequency volume chart, visual analogue score of symptoms, and King's Health Care Quality of life Questionnaire," described J. Rufford and colleagues, University of London Kings College Hospital, Department of Obstetrics & Gynecology.
"Forty women were included. Subjectively there was a significant improvement in urgency in both groups and urge incontinence in the estradiol group, but no significant differences between the groups. Objectively no significant differences were demonstrated between the groups."
"Nine women in ...
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Source: HighBeam Research, Estradiol implants don't improve the urge syndrome in postmenopausal...