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Exoerythrocytic stages of Plasmodium inui shortti shown in new world monkeys.

Vaccine Weekly

| September 03, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 SEP 3 - (NewsRx.com & NewsRx.net) -- Exoerythrocytic stages of Plasmodium inui shortti have been established in new world monkeys.

According to recent research published in the Journal of Parasitology, "Attempts are being made to adapt Old World monkey malarial parasites to New World monkeys for vaccine and molecular studies. Several of these (Plasmodium cynoniolgi Berok, Plasmodium fragile, and Plasmodium knowlesi) grow readily but have failed to produce infective gametocytes."

"Plasmodium gonderi and Plasmodium fieldi develop in the liver after sporozoite inoculation but have failed to establish infection in the erythrocyte," reported JoAnn S. Sullivan and colleagues at the Centers for Disease Control and Prevention in the United States. "Anopheles dirus mosquitoes infected with Plasmodium inui shortti by feeding on infected macaques transmitted the infection to Saimiri boliviensis monkeys. Infective gametocytes were produced, and sporozoite transmission from Saimiri to Saimiri monkey was obtained. Exoerythrocytic stages have also ...

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