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Tat-expressing Sendai viral vector-booster does not increase protection.
2003 SEP 3 - (NewsRx.com & NewsRx.net) -- No significant enhancement of protection by Tat-expressing Sendai viral vector-booster occurred in a macaque AIDS model.
According to a study from Japan, "We previously developed a DNA-prime/Gag-expressing Sendai virus (SeV) vector-boost vaccine system, and showed its excellent protective efficacy against a pathogenic SHIV infection in macaques. Alternative antigens may be used instead or together with Gag for the booster."
"We examined the potential of Tat as the booster antigen in our DNA-prime/SeV-boost system," reported Tetsuro Matano and colleagues at the University of Tokyo. "However, boosting by Tat-expressing SeV induced no significant enhancement of protection against SHIV infections."
- SYNTRO VIRAL VECTOR VACCINE APPROVED FOR FINAL TESTING
- Press release article from: PR Newswire April 4, 1994 700+ words
...field trials with the Company's first viral vector vaccine for poultry. The official USDA...the first commercial application of viral vector technology in any species. Evaluating...for the vaccine within six months. Viral vector technology is receiving increased attention...
- Viral vector-mediated endostatin transfer halts pancreatic cancer growth.
- Newspaper article from: Gastroenterology Week December 27, 2004 700+ words
2004 DEC 27 - (NewsRx.com & NewsRx.net) -- Viral vector-mediated endostatin transfer halts pancreatic cancer growth...published their study in Cancer Research (Adeno-associated viral vector-mediated expression of endostatin inhibits tumor growth...
- Puresyn Receives Second Phase II SBIR Grant; US Government Funds $750,000 for...
- Press release article from: PR Newswire June 21, 2002 700+ words
...grant Puresyn has received related to production-scale viral vector purification. Puresyn will employ its proprietary PolyFlo...for process-scale manufacturing of plasmid-based and viral vector- based gene therapies, and is introducing a new line of...
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- News wire article from: US Fed News Service, Including US State News November 9, 2009 700+ words
...subject's eye a dose of about 109 genome copies of an AAV7 viral vector and a minigene comprising sequences encoding the gene product...RPE65 protein in RPE cells and is delivered via the AAV7 viral vector." The invention carries International Patent Publication...
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- News wire article from: US Fed News Service, Including US State News October 12, 2009 700+ words
...Acton, Mass., have developed a method of using recombinant viral vector. The inventors were issued U.S. Patent No. 7,598...Office: "We have discovered that by using a recombinant viral vector, preferably a pox virus vector having at least one insertion...
- Vaporized viral vector shows promise in anti-cancer gene therapy.
- Newspaper article from: NewsRx Health June 28, 2009 700+ words
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- NEW ARTIFICIAL VIRAL VECTOR FROM JAPAN OFFERS SAFER GENE THERAPY.
- News wire article from: AsiaPulse News November 27, 2007 700+ words
TOKYO, Nov 27 Asia Pulse - A research team at Hokkaido University has developed an improved artificial viral vector for safely delivering genes into cells for gene therapy. Gene therapy now relies mainly on the adenovirus and other real viruses...
- Serial doses of aerosolized viral vector do well in nonhuman primates.
- Newspaper article from: Health & Medicine Week February 2, 2004 700+ words
2004 FEB 2 - (NewsRx.com & NewsRx.net) -- Serial doses of aerosolized viral vector do well in nonhuman primates. According to recent research published in the journal Molecular Therapy, "bronchoscopic microspraying...
Source: HighBeam Research, Tat-expressing Sendai viral vector-booster does not increase...