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Estrogens seem to calm the onset and effects of Parkinson disease.
2003 AUG 7 - (NewsRx.com & NewsRx.net) -- Estrogens seem to calm the onset and effects of Parkinson disease.
According to recent research published in the journal Endocrine, "epidemiologic studies revealed that the prevalence of Parkinson disease is higher in males than in females and that the progression of the disease might be rapid in males compared with females."
"The reason for the gender difference is unknown; however, estrogens may be involved. Many studies have revealed that estrogens provide neuroprotective effects and that the protective mechanisms include antioxidant property and upregulation of Bcl-2, brain-derived neurotrophic factor, and glial cell-derived neurotrophic factor (GDNF)," explained H. Sawada and colleagues, Kyoto University, Department of Neurology.
"Upregulation of Bcl-2 or GDNF is mediated by non-nuclear estrogen receptor (ER) in addition to ...
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Source: HighBeam Research, Estrogens seem to calm the onset and effects of Parkinson disease.