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New study finds red clover isoflavones help vaginal dryness in women at midlife.

Women's Health Weekly

| August 07, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 AUG 7 - (NewsRx.com & NewsRx.net) -- Results of a prospective, double-blind, placebo-controlled trial presented in London at the British Menopause Society annual meeting indicate that Novogen's red clover isoflavone supplement (Promensil) is a natural alternative for minimizing vaginal dryness in healthy, postmenopausal women.

As women get older, the vagina becomes dry and overly delicate in response to declining levels of the female hormone estrogen. About one in two postmenopausal women experience vaginal dryness and sensitivity. A normal part of aging, the dryness can be managed to help women avoid everyday discomfort and continue to enjoy sex.

The research - led by Dr. Malcolm Whitehead, director, gynecology/endocrinology unit, King's College Hospital, London - found that 80 mg of Promensil significantly improved the vaginal maturation index (VMI), a measure of normal functioning of the epithelium lining the vagina, compared to placebo, while there was no increase seen in endometrial thickening for either the Promensil or placebo groups.

"The preliminary results of this study are encouraging news for women who want to manage menopause naturally and to continue enjoying sex," said Whitehead. "Unlike steroidal estrogens, the natural isoflavone phytoestrogens or plant estrogens provided by the red clover supplement are showing a welcome estrogenic effect in relieving vaginal dryness while showing no adverse thickening effect on the endometrium."

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