AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
VEGF levels in normal human breast tissue vary during the menstrual cycle.
2003 AUG 7 - (NewsRx.com & NewsRx.net) -- VEGF levels in normal human breast tissue vary during the menstrual cycle.
"Exposure to sex steroids increases the risk of breast cancer, but the mechanisms are poorly understood. Angiogenesis is crucial in tumor development and progression. Very little is known about the regulation of angiogenesis in the normal breast," scientists in Sweden report.
"Vascular endothelial growth factor (VEGF) has a key stimulatory role in angiogenesis. Interferon-inducible protein 10 (IP-10) is a potent inhibitor of angiogenesis in vivo. These factors function in autocrine/paracrine pathways; therefore, direct measurements in the target tissue are needed," said C. Dabrosin, Linkoping University Hospital, Division of Gynecologic Oncology.
"I measured VEGF and IP-10 in normal human breast tissue in situ in healthy women, using microdialysis, in the follicular and luteal phase of the menstrual cycle. In breast tissue, VEGF levels increased in the luteal phase, compared with the follicular phase (17.8[+ or -]4 pg/ml to 34[+ or -]9 pg/ml, p
"Plasma VEGF did not show a cyclic variation (10.6[+ or -]2.8 pg/ml vs. 14.6[+ or -]3.5 pg/liter, p=0.3). IP-10 levels did not vary during the menstrual ...
- Genomics Collaborative and Celestar-Lexico Sciences to Develop Large-Scale...
- Press release article from: Business Wire March 31, 2004 700+ words
...profile of genes expressed in human breast cancer, utilizing Celestar...in gene expression between human breast cancer and normal breast tissue samples by applying the LisH...tested in tissue affected by human breast cancer and normal tissues...
- AVEO Pharmaceuticals Presents a Novel System for the Generation of Fully Human...
- Press release article from: PR Newswire April 4, 2006 700+ words
...Efficient generation of spontaneous human breast cancers in mice using defined...HIM system begins with normal human breast tissue that is genetically engineered...are critical to the formation of human breast cancer. The engineered cells...
- First murine experimental model developed of human breast cancer.
- Newspaper article from: Health & Medicine Week April 12, 2004 700+ words
...Research has successfully grafted human breast tissue into the mammary glands of mice...that are capable of producing human breast milk. More importantly, some...separated the two primary types of human breast tissue: epithelial cells, which form...
- Parabens are found in human breast tumors.
- Newspaper article from: Biotech Week March 24, 2004 700+ words
...Parabens are found intact within human breast tumors, with methylparaben showing...parabens can be extracted from human breast tissue and detected by thin-layer chromatography...individual parabens in samples of 20 human breast tumors by high-pressure liquid...
- New prognostic marker for human breast cancer.
- Magazine article from: Women's Health Weekly September 10, 2009 700+ words
...oncogene homolog 1) protein in human breast cancer are associated with unfavorable...unfavorable overall survival outcome in human breast cancer. This association has...along with samples of normal human breast tissue for comparison. As well as poor...
- Human breast cancer tissue microarrays. (Microarrays).
- Magazine article from: Bioscience Technology April 1, 2003 700+ words
Human breast cancer tissue microarrays (TMA) are offered for high throughput screening...represented. Hence, gene expression can be correlated with the normal breast tissue and breast cancer tissue, or with different stages of cancer development...
- Snapshot series may replace breast biopsy. (imaging technique distinguishes...
- Magazine article from: Science News Strauss, Evelyn July 5, 1997 700+ words
...MRI). This approach has the added benefit of working when breast tissue is too dense or scarred for mammography to be useful. MRI...Israel, and her colleagues first studied mice implanted with human breast tumor tissue and then assessed their method on patients...
- Mixtures of Four Organochlorines Enhance Human Breast Cancer Cell Proliferation.
- Magazine article from: Environmental Health Perspectives Payne, Joachim Scholze, Martin Kortenkamp, Andreas April 1, 2001 700+ words
...endocrine-related cancers such as neoplasms of the testis and prostate (1). In breast cancer, cumulative exposure of breast tissue to the endogenous hormone 17[Beta]-estradiol [1,3,5(10)-estratriene-3, 17[Beta]-diol] is thought...
Source: HighBeam Research, VEGF levels in normal human breast tissue vary during the menstrual...