AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Research methods could mask association with high fat intake.
2003 AUG 7 - (NewsRx.com & NewsRx.net) -- Imprecise methods of assessing dietary intake could be potentially obscuring a link between increased fat intake and breast cancer, suggest authors of a research letter in the July 18, 2003, issue of the Lancet.
Results of studies in which biological markers have been used as the reference method for assessment of dietary intake for selected nutrients suggest that the degree of error associated with food-frequency questionnaires (FFQs) is considerably larger than previously estimated. This could explain the lack of an association between increased fat intake and breast cancer in population studies.
Sheila Bingham from the MRC Dunn Human Nutrition Unit, Cambridge, U.K., and Cambridge University colleagues assessed the relation between breast-cancer risk and fat intake with an FFQ similar to those used in previous population (cohort) studies and a 7-day food diary completed by women in the European Prospective Investigation of Cancer and Nutrition (EPIC) Norfolk study.
Around 13,000 women were studied using a FFQ and 7-day food diary between 1993 and 1997. Of these, 168 had developed breast cancer by the year 2000, at which time analysis of fat intake was assessed for each woman with breast cancer compared with four healthy controls matched for age and other factors to take account of possible bias.
Women in the upper quintile (top 20%) for saturated-fat consumption were at twice the risk of breast cancer than women in the lowest quintile when fat intake was assessed by the food diary; however no association was evident between increased saturated fat intake and breast-cancer risk with use of the FFQ.
Specifically, the researchers found that women who had eaten more than 90 g of fat per day had twice the risk of breast cancer of those who had eaten less than 40 g of fat per day.
"Inconsistency between experimental and epidemiological data on fat and breast-cancer risk could thus be accounted for by problems with methods used in cohort studies to measure diet. The food diary is more expensive to code for conversion into nutrients than the FFQ, but we have shown that its use is acceptable and feasible in large cohort studies," said Bingham.
- Clinical Briefs: Fat Intake and Breast Cancer Risk.
- Newspaper article from: Alternative Medicine Alert March 1, 2004 700+ words
...H. Greenfield, MD Fat Intake and Breast Cancer Risk Source: Cho E, et al. Premenopausal fat intake and risk of breast cancer. J Natl Cancer Inst...relationship between dietary fat intake and breast cancer risk in premenopausal...
- The Role of Fat Intake in Breast Cancer.
- Newspaper article from: Alternative Therapies in Women's Health July 1, 2004 700+ words
The Role of Fat Intake in Breast Cancer By Lynn Keegan, RN...question as to whether high fat intake increases the risk of breast cancer has been quite controversial...mechanism of action of fat intake on breast cancer is likely to be different...
- Health Tip: High-Fat Intake Correlates With Breast Cancer
- Newspaper article from: New York Beacon, The Laurie Asseo May 10, 1995 700+ words
...Health Tip: High-Fat Intake Correlates With Breast Cancer. Not only what people...important in preventing breast cancer. Specifically, people...between high dietary fat intake and increased risk of breast cancer, as well as certain...
- Higher dietary fat intake is associated with an increased breast cancer risk.
- Newspaper article from: Drug Week January 23, 2004 700+ words
...increased risk of breast cancer. "Animal experiments...suggest that dietary fat intake is associated with a risk of breast cancer, but individual...and saturated fat intake, and for meat...increased risk of breast cancer. Case-control...
- Breast Ca Risk Appears Unrelated To Fat Intake.(Brief Article)(Statistical Data...
- Magazine article from: Family Practice News Moon, Mary Ann June 15, 1999 700+ words
...decrease in risk of breast cancer, compared with women with an average fat intake. Breast cancer risk did not rise...reductions in total fat intake during midlife are unlikely to prevent breast cancer and should receive...
- High vegetable fat intake in teen years may reduce breast Ca risk: nurses'...
- Magazine article from: OB GYN News Jancin, Bruce February 1, 2004 700+ words
...greater dietary fat intake accounted for...incidence of breast cancer in the Unit...association between fat intake and breast cancer risk, an international...for vegetable fat intake had a 39% reduction...relative risk of breast cancer. ...
- Soy Isoflavones in the Management of Breast Cancer Survivors: A Judgment Call.
- Magazine article from: Townsend Letter for Doctors and Patients Hudson, Tori October 1, 2001 700+ words
...the capacity to examine breast cancer risk at the extremes of fat intake is limited by the small...association between saturated fat intake and breast cancer risk, but no association with monounsaturated fat intake. Another study in France...
- Breast cancer considerations to assist the practitioner in clinical...
- Magazine article from: Townsend Letter for Doctors and Patients Hudson, Tori June 1, 2002 700+ words
...the capacity to examine breast cancer risk at the extremes of fat intake is limited by the small...association between saturated fat intake and breast cancer risk, but no association with monounsaturated fat intake. Another study in France...
Source: HighBeam Research, Research methods could mask association with high fat intake.