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2003 AUG 7 - (NewsRx.com & NewsRx.net) -- Breast cancer worry and risk were determinants of prophylactic mastectomy.
"Scientific reports suggest that women at risk for familial breast cancer may benefit from prophylactic mastectomy," researchers in Netherlands report.
"However, few data are available about how women decide upon this clinical option, and in particular, what role an objective risk assessment plays in this. The purpose of the present study is to assess whether this objective risk information provided in genetic counseling affects the intention for prophylactic mastectomy," wrote S. VanDijk and colleagues, Leiden University, Department of Medical Decision Making.
"Additionally, the (mediating) effects of breast cancer worry and perceived risk are investigated. A total of 241 women completed a questionnaire before and after receiving information about their familial lifetime breast cancer risk in a genetic counseling session," the researchers wrote.
"Path analysis showed that the objective risk information had a corrective effect on perceived risk (beta = 0.38; p=.0001), whereas the amount of breast cancer worry was not influenced by the counseling session," the researchers stated.
"The objective risk information did not directly affect the intention for prophylactic mastectomy. The intention was influenced by perceived risk after counseling (beta = 0.23; p=.002), and by the precounseling levels of perceived risk (beta = 0.27; p=.00025) and breast cancer worry (beta = 0.32; p=.0001); that is, higher levels of perceived risk and breast cancer worry imply a stronger intention for prophylactic mastectomy," the researchers wrote.
"A personal history ...
Source: HighBeam Research, Breast cancer worry and risk were determinants of prophylactic...