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Antigenic cross-reactivity between measles and cowpea mosaic viruses found.

Vaccine Weekly

| August 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 AUG 6 - (NewsRx.com & NewsRx.net) -- Antigenic cross-reactivity was found between measles and cowpea mosaic viruses.

"Two nonrelated viruses, cowpea mosaic virus (wtCPMV) and measles virus (MV), were found to induce cross-reactive antibodies. The nature of this cross-reactivity was studied and results are presented here demonstrating that antiserum raised against wtCPMV reacted with peptide from the fusion (F) protein of MV. Furthermore, the F protein of MV was shown to share an identical conformational B cell epitope with the small subunit of CPMV coat protein," scientists in England report.

"Passive transfer of anti-wtCPMV antibodies into BALB/c mice conferred partial protection against measles virus induced encephalitis," stated Wieslawa Olszewska and Michael W. Steward at the London School of Hygiene and ...

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