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Heart Association comments on patients with dilated cardiomyopathy following vaccine.

Vaccine Weekly

| August 06, 2003 | COPYRIGHT 2003 NewsRX. This material is published under license from the publisher through the Gale Group, Farmington Hills, Michigan.  All inquiries regarding rights should be directed to the Gale Group. (Hide copyright information)Copyright

2003 AUG 6 - (NewsRx.com & NewsRx.net) -- The U.S. Centers for Disease Control and Prevention has reported that two patients contracted dilated cardiomyopathy (DCM) 3 months after receiving the smallpox vaccine. Smallpox vaccinations have not been previously associated with DCM.

According to Augustus O. Grant, MD, PhD, American Heart Association president, these two adverse event reports should raise awareness that an inflammatory reaction from the vaccine could be a potential mediating factor in cardiomyopathy. Myocarditis, which involves an inflammatory reaction, has been seen in increased numbers in patients receiving smallpox vaccination.

However, in roughly half of all investigated cases of DCM, there is no identified cause, and even pinpointing the time that heart dysfunction began can be difficult. With only two cases reported out of 38,000 vaccinations, it is not possible to determine if the smallpox vaccine caused the DCM.

DCM is a type of heart disease characterized by an enlarged, poorly functioning heart ...

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