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R&D agreement initiated with U.S. Army for oral anthrax vaccine.
2003 JUL 16 - (NewsRx.com & NewsRx.net) -- Emisphere Technologies, Inc., (EMIS) announced that it has signed a cooperative research and development agreement (CRADA) with the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID), the U.S. Department of Defense's lead laboratory for medical aspects of biological warfare defense.
USAMRIID will evaluate the use of Emisphere's eligen technology to create oral vaccines against anthrax using a new recombinant protein antigen.
Under the CRADA agreement, Emisphere will provide the USAMRIID's Fort Detrick site in Frederick, Maryland with oral formulations containing Emisphere delivery agents and the recombinant anthrax antigen. USAMRIID will conduct all in vivo experiments. The formulations will use Emisphere's eligen technology, a broad-based oral drug delivery technology platform that enables the transport of the therapeutic molecules across biological membranes, including the gastrointestinal tract, without altering their chemical form or biological integrity.
USAMRIID has agreed to grant Emisphere an exclusive license to each U.S. patent application or issued patent as a result of the work performed under the CRADA. Should an oral anthrax vaccine ultimately be developed, Emisphere would be eligible to receive royalties under a license agreement with the ultimate vaccine developer.
Vivien Wong, PhD, Emisphere's senior director, proof-of-concept studies, stated, "The initiation of oral vaccine proof-of-concept studies to defend Americans against the risk of anthrax is a valuable addition to our proof-of-concept portfolio. For Emisphere, it broadens the application of our eligen technology to a new and important area of vaccines and infectious ...
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Source: HighBeam Research, R&D agreement initiated with U.S. Army for oral anthrax vaccine.