AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Bacille Calmette-Guerin vaccine may improve immunity against other infections.
2003 JUL 9 - (NewsRx.com & NewsRx.net) -- by Michael Greer, senior medical writer - The bacille Calmette-Guerin (BCG) tuberculosis vaccine may improve immunity against other infections as well, researchers say.
Results from other studies indicated that the BCG vaccine "may have a non-specific beneficial effect on childhood survival in areas with high mortality," explained May-Lill Garly and colleagues at the Projecto de Saude de Bandim in Bissau, Guinea-Bissau, the Medical Research Council Laboratories in Banjul, Gambia, and the Statens Serum Institute in Copenhagen, Denmark.
Garly and coauthors found that BCG-vaccinated children in a high-mortality area had a significantly lower risk of death and that this effect was independent of tuberculosis protection.
Among children participating in a measles vaccine study, those with a BCG scar had a mortality rate less than half that of the counterparts, the researchers said. Moreover, BCG-vaccinated children with hypersensitivity reactions to tuberculin had a mortality rate less than half that of immunized children without such reactions.
Excluding children with tuberculosis exposure did not significantly affect the impact of BCG scar or tuberculin positivity on mortality risk, study data showed. The exclusion of dead HIV-seropositive children also left the mortality ratio unchanged.
...- Bacille Calmette-Guerin vaccine may improve immunity against other infections.
- Newspaper article from: TB & Outbreaks Week July 8, 2003 700+ words
...explained May-Lill Garly and colleagues at...study, those with a BCG scar had a mortality...mortality risk (BCG scar and positive tuberculin...2790). "Thus, BCG scar and a positive tuberculin...report is May-Lill Garly, Projecto de Saude...
- Tuberculin reactions in apparently healthy HIV-seropositive and...
- Newspaper article from: Morbidity and Mortality Weekly Report September 21, 1990 700+ words
...seronegative women, 18 (56%) had a BCG scar; of the 61 HIV-seropositive women, 28 (46%) had a BCG scar. For both HIV-seronegative and HIV...was more likely among those without a BCG scar. Among the HIV-seronegative women...
- Investigators at Indian Council of Medical Research publish new data on life...
- Newspaper article from: Biotech Week October 8, 2008 700+ words
...read after 72 h." "The proportion of BCG scar-positive children was 34.6%. The...infection among children irrespective of BCG scar was estimated as 20.4% (95% CI 18...9% (95% CI 3.4-4.5%) among BCG scar-negative children and 19.0% (95...
- London, Oct 18 (PTI): The BCG vaccine offers more protection against...
- News wire article from: PTI - The Press Trust of India Ltd. October 18, 2005 700+ words
...infection. Of these children, 770 had a BCG scar, indicating that they had been vaccinated...test results, they found absence of a BCG scar was a strong, independent risk factor for TB infection while the presence of a BCG scar was associated with a 24 per cent reduction...
- Vaccine-induced immunity circumvented by typical Mycobacterium tuberculosis...
- Magazine article from: Emerging Infectious Diseases Kremer, Kristin van der Werf, Marieke J. Au, Betty K.Y. Anh, Dang D. Kam, Kai M. van Doorn, H. Rogier Borgdorff, Martien W. van Soolingen, Dick February 1, 2009 700+ words
...In a study in Ho Chi Minh City, Vietnam, presence of a BCG scar correlated, but not significantly, with infection by Beijing...susceptibility data and BCG status of patients (presence/absence of BCG scar) were not available from Hong Kong. The patients in this...
- Statistical model useful for determining prevalence of TB in people with BCG...
- Newspaper article from: Vaccine Weekly June 26, 2002 700+ words
...significant difference existed between the prevalence of tuberculosis (TB) infection in people with a Bacillus Calmette-Guerin (BCG) scar and those without such a scar, say researchers in Switzerland. BCG is used as a vaccine to prevent tuberculosis where the...
- Tuberculin response higher in BCG-vaccinated children with allergic diseases.
- Newspaper article from: Immunotherapy Weekly December 11, 2002 700+ words
...difference between the two groups was significant (p<0.001)," Ozmen's group reported. "In children with a single BCG scar, the mean purified protein derivative (PPD) wheal size for allergic children was 4.77 [+ or -] 4.79 mm, and for nonallergic...
- Mycobacterium tuberculosis Beijing Genotype Emerging in Vietnam.(Statistical...
- Magazine article from: Emerging Infectious Diseases Anh, Dang Duc Borgdorff, Martien W. Van, L.N. Lan, N.T.N. van Gorkom, Tamara Kremer, Kristin van Soolingen, Dick May 1, 2000 700+ words
...25 76 54 (71) 25-34 173 102 (59) 35-44 164 83 (51) 45-54 74 31 (42) 55-64 39 16 (41) 65+ 37 15 (41) BCG scar Yes 285 167 (59) No 278 134 (48) Total 563 301 (54) OR(a) (95% CI(b) Crude Adjusted(c) Province Hanoi 1...