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Ocular complications of smallpox and smallpox immunization outlined.
2003 JUL 9 - (NewsRx.com & NewsRx.net) -- The ocular complications of smallpox and smallpox immunization have been outlined in a recent issue of Archives of Ophthalmology.
"Although smallpox was eradicated worldwide, concerns have been raised about the use of smallpox as a biological weapon. Plans are being considered for smallpox immunization in the United States. Variola virus, the cause of smallpox, and vaccina virus, used in smallpox immunization, are both orthopoxviruses that are associated with serious ocular complications, including eyelid and conjunctival infection, corneal ulceration, disciform keratitis, iritis, optic neuritis, and blindness," a researcher in the United States reports.
"About 5% to 9% of patients with smallpox develop ocular complications, and case-fatality rates reach 20% to 35% among unvaccinated individuals," stated Richard D. Semba at the Wilmer Eye Institute located at The Johns Hopkins University. "About 10 to 20 patients develop ocular complications per one million smallpox immunizations, usually through autoinoculation, in which the patient transfers vaccinia from the immunization site to the eye."
"The risk of ocular vaccinia infection may be reduced by ...
- Ocular complications of smallpox and smallpox immunization outlined.
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