AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Modified merozoite surface protein immunogenic.
2003 JUL 9 - (NewsRx.com & NewsRx.net) -- A modified plasmodial peptide could be the basis for a malaria vaccine.
"The conserved, nonantigenic, nonimmunogenic malaria merozoite surface protein-2 peptide 1, having high affinity for red blood cells, was rendered immunogenic and protective in Aotus monkeys by specifically changing some critical residues," according to G. Cifuentes and colleagues at the Fundacion Instituto de Inmunologia de Colombia.
"The NMR structure revealed a switch from classical type III' into distorted III' and III beta turns in the protective peptides," they reported.
"These changes may lead to a better fit into the Aotus MHC class II human HLA-DRbeta1*0102 molecule equivalent, thus activating the immune system," the ...
- Modified merozoite surface protein immunogenic.
- Newspaper article from: Malaria Weekly (Atlanta, GA) July 7, 2003 700+ words
...nonantigenic, nonimmunogenic malaria merozoite surface protein-2 peptide 1, having high...published their study in the Journal of Medicinal Chemistry (Distorting malaria peptide backbone...contact information for the Journal of Medicinal Chemistry is: American Chemical Society...
- Merozoite surface protein peptides associated with malaria protection.
- Newspaper article from: Biotech Week November 19, 2003 700+ words
...amp; NewsRx.net) -- Modified merozoite surface protein-1 peptides with short alpha...protection against malaria. "The merozoite surface protein-1 represents a prime candidate...development of a malaria vaccine. Merozoite surface protein-1 has been shown to demonstrate...
- Merozoite surface protein antibodies inhibit malaria antibody responses.
- Newspaper article from: Drug Week June 25, 2004 700+ words
...C-terminal region of merozoite surface protein-1-specific...C-terminal region of merozoite surface protein-1-specific...C-terminal region of merozoite surface protein-1 (MSP1[subscript...
- Plasmodium merozoite surface protein-2 promoter identified.
- Newspaper article from: Health & Medicine Week September 15, 2003 700+ words
...identified. "Plasmodium falciparum merozoite surface protein (MSP)-2 is a polymorphic...immediately 3' of the gene encoding merozoite surface protein-5 (MSP-5) with a 1096...FC27 allelic forms of MSP-2 at the merozoite surface." "These results have identified...
- Merozoite surface antigen 2 gene from Plasmodium falciparum sequenced.
- Newspaper article from: Biotech Week June 25, 2003 700+ words
...com & NewsRx.net) -- The merozoite surface antigen 2 gene from Plasmodium falciparum...protective antigens, the gene encoding merozoite surface antigen 2 (MSA2) was amplified...Molecular cloning and sequencing of the merozoite surface antigen 2 gene from Plasmodium falciparum...
- Merozoite surface protein antibodies protect against malaria infection.
- Newspaper article from: TB & Outbreaks Week August 24, 2004 700+ words
...specific for the 19-kDa fragment of merozoite surface protein-1 (MSP-1[subscript...fragment of Plasmodium falciparum merozoite surface protein-1 (MSP-1[subscript...specific for the 19-kDa fragment of merozoite surface protein-1 (MSP-1[subscript...
- Merozoite surface proteins differ in ability to protect against malaria.
- Newspaper article from: Medical Letter on the CDC & FDA May 2, 2004 700+ words
...NewsRx.net) -- Members of the merozoite surface protein 7 family with similar expression...related molecules P. yoelii MSP-7 (merozoite surface protein 7) and P. yoelii MSRP...Infection and Immunity (Members of the merozoite surface protein 7 family with similar expression...
- Malaria parasite merozoite surface protein 1 complex shows vaccine promise.
- Newspaper article from: Vaccine Weekly August 27, 2003 700+ words
...com & NewsRx.net) -- The merozoite surface protein 1 complex of the malaria...stage malaria parasites, is the merozoite surface protein 1 (MSP-1) complex. In...Journal of Biological Chemistry (The merozoite surface protein 1 complex of human malaria...
