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Reverse vaccinology allows development of novel vaccines.
2003 JUL 9 - (NewsRx.com & NewsRx.net) -- The concept of reverse vaccinology is discussed in a recent issue of Drug Discovery Today.
"Whole-genome sequencing of bacteria and advances in bioinformatics have revolutionized the vaccinology field, leading to the identification of potential vaccine candidates without the need for cultivating the pathogen. This approach, termed 'reverse vaccinology,' reduces the time and cost required for the identification of candidate vaccines and provides new solutions for those diseases for which conventional approaches have failed," scientists writing in the journal Drug Discovery Today report.
"The first example of the potential of reverse vaccinology has been the identification of novel antigens of meningococcus B as potential candidates for a novel and effective vaccine," said Marirosa Mora and colleagues at Chiron S.r.l. in Siena. "The same approach has been successfully applied to ...
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