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Competition Heats Up For New Cancer Drugs.(THE NEW AMERICA)(Q & A)
Byline: GLORIA LAU
The fight against cancer has taken plenty of turns through the years. One thing has remained constant, however: there's still no cure.
Targeted drugs don't cure cancer, either. But they do have at least one advantage over treatments such as chemotherapy: they fight the disease without harming nearby healthy cells. In some cases they've prolonged lives or shrunk deadly tumors.
Over recent months, several new cancer drugs have won approval from the Food and Drug Administration.
In May, Millennium Pharmaceuticals Inc. got FDA approval to start marketing Velcade, its drug for multiple myeloma patients who've received at least two prior failed treatments.
Last year's list of approvals included Novartis AG's Gleevec for leukemia and Zometa for prostate and bone cancer; AstraZeneca PLC's Iressa for lung cancer and Arimdex and Faslodex for breast cancer; and Sanofi Synthelabo's Eloxatin for colon and rectal cancers.
More drugs are on the way. The current drug pipeline includes Genentech Inc.'s Avastin; Cell Therapeutics Inc.'s Xyotax for lung and ovarian cancer; and OSI Pharmaceuticals' Tarceva for lung and pancreatic cancer.
- FDA Approves Novartis Drug Gleevec(TM) (imatinib mesylate)* for a...
- Press release article from: PR Newswire February 1, 2002 700+ words
...either 400 mg or 600 mg of Gleevec daily for up to 24 months...off for the submission. Gleevec, a signal transduction inhibitor, is one of the first cancer drugs to be developed using rational...how some cancer cells work. Gleevec targets the activity of certain...
- Phase I Data on Gleevec(TM) (imatinib mesylate)* for Treatment of Patients With...
- Press release article from: PR Newswire October 26, 2001 700+ words
...Switzerland and Australia. Gleevec received a positive recommendation...Commission is anticipated shortly. Gleevec is one of the first cancer drugs to be developed using rational...how some cancer cells work. Gleevec is believed to target the activity...
- Novartis Submits Supplemental NDA with U.S. Food and Drug Administration for...
- Press release article from: PR Newswire October 19, 2001 700+ words
...the patient becomes pregnant while taking Gleevec, the patient should be apprised of the potential...There are no long-term safety data on Gleevec treatment. Gleevec is one of the first cancer drugs to be developed using rational drug design...
- WHEN LESS IS MORE REDUCED SPECIFICITY KEY TO FIGHTING GLEEVEC...
- Magazine article from: BIOWORLD Today Breindl, Anette December 9, 2004 700+ words
...Anette Breindl, Science Editor Gleevec is a beacon of sorts, a herald...medicine. It was one of the first cancer drugs to target a specific molecular...features such as dividing cells. Gleevec binds to the active form of...chromosome 9 and 22 trade places. Gleevec, made by Novartis AG, of...
- FDA approves Gleevec for GI cancer.
- Newspaper article from: Drug Week March 15, 2002 700+ words
...either 400 mg or 600 mg of Gleevec daily for up to 24 months...off for the submission. Gleevec, a signal transduction inhibitor, is one of the first cancer drugs to be developed using rational...how some cancer cells work. Gleevec targets the activity of certain...
- FDA approves Gleevec for GI cancer.(Brief Article)
- Newspaper article from: Cancer Weekly March 19, 2002 700+ words
...either 400 mg or 600 mg of Gleevec daily for up to 24 months...off for the submission. Gleevec, a signal transduction inhibitor, is one of the first cancer drugs to be developed using rational...how some cancer cells work. Gleevec targets the activity of certain...
- Risks of cancer drug explored: Study says Gleevec, a treatment for leukemia,...
- Newspaper article from: Newsday (Melville, NY) July 24, 2006 700+ words
...year. "Prior to going on Gleevec, they were all normal...What it's intended to do Gleevec, one of the first in the growing class of targeted cancer drugs, is a dramatic departure...enzyme into wild overdrive. Gleevec blocks the enzyme, but...
- Gleevec.(result of clinical trials for cancer drug)
- Magazine article from: Townsend Letter for Doctors and Patients Klotter, Jule August 1, 2001 700+ words
...reported a remarkable response to Gleevec among patients with advanced...not all patients responded to Gleevec, the number of remissions...People article stated that Gleevec's side effects were "minimal...resistance to the drug. "Targeted Cancer Drugs" www.sciencefriday.com...
