AccessMyLibrary provides FREE access to over 30 million articles from top publications available through your library.
Create a link to this page
Copy and paste this link tag into your Web page or blog:
Circulating tumor cells in peripheral blood predict poor survival.
2003 JUL 3 - (NewsRx.com & NewsRx.net) -- Circulating tumor cells in peripheral blood predict poor survival.
"We investigated the prognostic significance of circulating breast cancer cells in peripheral blood detected by quantitative RT-PCR of marker genes in patients with advanced breast cancer," scientists in Netherlands report.
"Blood samples from 94 breast cancer patients with metastatic disease (MI) were examined for circulating tumor cells by studying the mRNA expression of CK 19, pIB, PS2 and EGP2 by real-time PCR," wrote B. Weigelt and colleagues, Netherlands Cancer Institute, Department of Pathology.
"Using a score function developed for predicting circulating tumor cells by quadratic discriminant analysis (QDA), the four expression levels were combined into a single discriminant value. Tumor cells were present in 24 out of 94 (31%) of the patients," the researchers wrote.
"In 77% (72 out of 94) of the patients distant metastatic disease was localized in the bone. In 36% (26 out of 72) of the patients with bone metastases at the time of blood sampling, a positive QDA for the four genes was found, in contrast to only 14% (three out of 22) without bone involvement," the researchers stated.
"Overall survival rates by Kaplan-Meier revealed no ...
- Applied Imaging Forms a Subsidiary to Develop Advanced Technology for Detecting...
- Press release article from: PR Newswire August 10, 2004 700+ words
...of a subsidiary, called Circulating Tumor Cells, Inc. (CTC), to research...and products for detecting circulating tumor cells (CTCs) in peripheral blood...reagent technology to isolate circulating tumor cells in the blood of cancer patients...
- Applied Imaging forms subsidiary to develop advanced technology for detecting...
- Newspaper article from: BIOTECH Patent News August 1, 2004 700+ words
...of a subsidiary, called Circulating Tumor Cells, Inc. (CTC), to research...and products for detecting circulating tumor cells (CTCs) in peripheral blood...reagent technology to isolate circulating tumor cells in the blood of cancer patients...
- Quest Diagnostics to Offer New Test to Measure Circulating Tumor Cells in...
- Press release article from: PR Newswire September 20, 2004 700+ words
...that identifies and counts circulating tumor cells in blood samples from patients...demonstrated that the number of circulating tumor cells is predictive of progression...used for the enumeration of circulating tumor cells of epithelial origin in...
- Level of Circulating Tumor Cells in Bloodstream Predicts Breast Cancer...
- Press release article from: PR Newswire August 18, 2004 700+ words
...the body, the level of circulating tumor cells in the bloodstream before...suggest that the presence of circulating tumor cells can shed light on the prognosis...based on their levels of circulating tumor cells. People in the unfavorable...
- Immunicon Corporation Announces Presentation of Data on Circulating Tumor Cells...
- Press release article from: PR Newswire May 17, 2005 700+ words
...and the significance of circulating tumor cells (CTCs) versus serum tumor...The abstract entitled: "Circulating tumor cells -- not serum tumor markers...the presence of 5 or more circulating tumor cells (CTCs) in a 7.5mL sample...
- Immunicon Corporation Announces Presentation of Data on Circulating Tumor Cells...
- Press release article from: PR Newswire May 16, 2005 700+ words
...and the significance of circulating tumor cells (CTCs) in "non-measurable...entitled: "Monitoring circulating tumor cells (CTC) in non-measurable...the presence of 5 or more circulating tumor cells (CTCs) in a 7.5mL sample...
- OncoGenex Pharmaceuticals Announces OGX-427 Treatment Demonstrates Safety,...
- Press release article from: PR Newswire May 30, 2009 700+ words
...demonstrated declines in circulating tumor cells at all doses evaluated as...markers. Reductions in circulating tumor cells and tumor markers both suggest...and Tumor Marker Results Circulating tumor cells (CTCs), an emerging metric...
- Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast...
- Newspaper article from: Clinical Oncology Alert November 1, 2004 700+ words
Circulating Tumor Cells, Disease Progression, and Survival...Commentary Synopsis: The number of circulating tumor cells before treatment is an independent...metastatic breast cancer for levels of circulating tumor cells both before and after the initiation...
Source: HighBeam Research, Circulating tumor cells in peripheral blood predict poor survival.